Mpc1
Gene Detail

Symbol Name ID

Mpc1 mitochondrial pyruvate carrier 1 MGI:1915240

Synonyms

0610006G08Rik, 3830411I18Rik, Brp44l

Feature Type

protein coding gene

Genetic Map

Chromosome 17

4.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr17:8282904-8297661 bp, + strand From VEGA annotation of GRCm38   14758 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mpc1

Human homologs

Human Homolog		MPC1, mitochondrial pyruvate carrier 1
NCBI Gene ID		51660
neXtProt AC		NX_Q9Y5U8
Human Synonyms		BRP44L, dJ68L15.3, MPYCD
Human Chr (Location)		6q27; chr6:166778407-166796501 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MPC1

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	mitochondrial pyruvate transport, pyruvate metabolic process, ...
Component	integral to membrane, intracellular, ...
Function	pyruvate transmembrane transporter activity

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (120)    Tissues (42)    Images (38)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	120

cDNA source data(173)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(175) cDNA(174) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000032995 (Evidence)
Ensembl Gene Model	ENSMUSG00000023861 (Evidence)
Entrez Gene	55951 (Evidence)
UniGene	288510
DFCI	TC1573511, TC1628215, TC1732055, TC1774406
DoTS	DT.101223813, DT.537241, DT.91337836, DT.94202365, DT.99867565
NIA Mouse Gene Index	U017467, U088289
Consensus CDS Project	CCDS49944.1
International Mouse Knockout Project Status	Mpc1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032995	VEGA Gene Model | MGI Sequence Detail	14758	C57BL/6J
transcript	OTTMUST00000082288	VEGA | MGI Sequence Detail	961	Not Applicable
polypeptide	OTTMUSP00000044089	VEGA | MGI Sequence Detail	167	Not Applicable

All sequences(68) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(96 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005336	Uncharacterised protein family UPF0041
Protein Ontology	PR:000004821	brain protein 44-like protein

References

(Earliest) J:58544 Trachtulec Z, et al., Synteny of orthologous genes conserved in mammals, snake, fly, nematode, and fission yeast. Mamm Genome. 2001 Mar;12(3):227-31
(Latest) J:185358 Herzig S, et al., Identification and functional expression of the mitochondrial pyruvate carrier. Science. 2012 Jul 6;337(6090):93-6
All references(35)

Other accession IDs

MGI:1917947