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Ero1lb Gene Detail
Summary
  • Symbol
    Ero1lb
  • Name
    ERO1-like beta (S. cerevisiae)
  • Synonyms
    1300013B24Rik, 1700065B09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914725
    NCBI Gene: 67475
  • Gene Overview
    MyGene.info: ERO1B
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:12565808-12609533 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    494 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914725
protein coding gene Chr13:12565808-12611396 (.)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020189
protein coding gene Chr13:9153496-9211680 (+)
AKR/J MGP_AKRJ_G0020164
protein coding gene Chr13:9358365-9402157 (+)
BALB/cJ MGP_BALBcJ_G0020172
protein coding gene Chr13:9138853-9193571 (+)
C3H/HeJ MGP_C3HHeJ_G0019976
protein coding gene Chr13:9493800-9555849 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020619
protein coding gene Chr13:9762083-9870203 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018226
protein coding gene Chr13:8984272-9027472 (+)
CAST/EiJ MGP_CASTEiJ_G0019514
protein coding gene Chr13:9202097-9295205 (+)
CBA/J MGP_CBAJ_G0019943
protein coding gene Chr13:10019019-10114032 (+)
DBA/2J MGP_DBA2J_G0020060
protein coding gene Chr13:8977815-9033285 (+)
FVB/NJ MGP_FVBNJ_G0020045
protein coding gene Chr13:8791928-8837209 (+)
LP/J MGP_LPJ_G0020134
protein coding gene Chr13:9431312-9496432 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020081
protein coding gene Chr13:10313858-10391188 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020647
protein coding gene Chr13:9254186-9293695 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019084
protein coding gene Chr13:9249107-9296022 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ERO1B, endoplasmic reticulum oxidoreductase 1 beta
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ERO1B, endoplasmic reticulum oxidoreductase 1 beta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Ero1beta, ERO1LB
  • Links
    NCBI Gene ID: 56605
    neXtProt AC: NX_Q86YB8
    UniProt: Q86YB8

  • Chr Location
    1q42.3; chr1:236215122-236282039 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    1 images
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit increased circulating glucose levels, decreased pancreas insulin levels, and disorganized islets.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67475 NCBI Gene Model | MGI Sequence Detail 43726 C57BL/6J ±  kb
transcript NM_026184 RefSeq | MGI Sequence Detail 4255 C57BL/6  
polypeptide Q8R2E9 UniProt | EBI | MGI Sequence Detail 467 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 68

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920689, MGI:2145237
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:250104 Flodby P, et al., The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory