Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein-disulfide reductase activity. Involved in insulin processing. Acts upstream of or within several processes, including cell redox homeostasis; glucose homeostasis; and protein maturation by protein folding. Located in membrane. Is active in endoplasmic reticulum lumen. Is expressed in heart and hindlimb joint. Orthologous to human ERO1B (endoplasmic reticulum oxidoreductase 1 beta).