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Dhdds
Gene Detail
Symbol

Name
ID
Dhdds
dehydrodolichyl diphosphate synthase
MGI:1914672
Synonyms
3222401G21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
66.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:133969028-134000918 bp, - strand
From VEGA annotation of GRCm38

  31891 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32615  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DHDDS
Protein SuperFamily: cis-prenyltransferase
Gene Tree: Dhdds

Human
homologs
DHDDS, dehydrodolichyl diphosphate synthase subunit
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 79947
neXtProt AC: NX_Q86SQ9

Human Synonyms: CIT, CPT, DS, HDS, RP59

Human Chr (Location): 1p36.11; chr1:26432282-26471306 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DHDDS

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Genomic Mutations involving Dhdds (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Dhdds interacts with 301 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process biological_process
Component endoplasmic reticulum, membrane
Function polyprenyltransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(105)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dhdds ; ZFIN dhdds    NEW 
Molecular
reagents
All nucleic(105) cDNA(105)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000009801 (Evidence)
Ensembl Gene Model ENSMUSG00000012117 (Evidence)
Entrez Gene 67422 (Evidence)
UniGene 100290
DFCI TC1579762, TC1576733, TC1615878, TC1604659, TC1616407
DoTS DT.101380081, DT.97366434, DT.55113480
NIA Mouse Gene Index U025629
EC 2.5.1.87
Consensus CDS Project CCDS18760.1
International Mouse Phenotyping Consortium Status Dhdds
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009801 VEGA Gene Model | MGI Sequence Detail 31891 C57BL/6J ±  kb
transcript OTTMUST00000023336 VEGA | MGI Sequence Detail 2038 Not Applicable 
polypeptide OTTMUSP00000010668 VEGA | MGI Sequence Detail 334 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(12) UniProt(5)
Polymorphisms
SNPs within 2kb(307 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001441 Decaprenyl diphosphate synthase-like
InterPro IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site
Protein Ontology PR:000006455 dehydrodolichyl diphosphate synthase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:2140720

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory