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Smarcd3 Gene Detail
Summary
  • Symbol
    Smarcd3
  • Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  • Synonyms
    1500001J14Rik, 2210409C08Rik, BAF60C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914243
    NCBI Gene: 66993
  • Gene Overview
    MyGene.info: SMARCD3
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:24592622-24624456 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 11.93 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914243
protein coding gene Chr5:24590818-24624456 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029352
protein coding gene Chr5:22338359-22377149 (-)
A/J MGP_AJ_G0029318
protein coding gene Chr5:21565480-21598879 (-)
AKR/J MGP_AKRJ_G0029269
protein coding gene Chr5:22430415-22465496 (-)
BALB/cJ MGP_BALBcJ_G0029329
protein coding gene Chr5:22081246-22115169 (-)
C3H/HeJ MGP_C3HHeJ_G0029049
protein coding gene Chr5:22549532-22582638 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029782
protein coding gene Chr5:23838916-23872040 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027020
protein coding gene Chr5:19507217-19540757 (-)
CAST/EiJ MGP_CASTEiJ_G0028461
protein coding gene Chr5:21735189-21770391 (-)
CBA/J MGP_CBAJ_G0029016
protein coding gene Chr5:24224697-24259752 (-)
DBA/2J MGP_DBA2J_G0029167
protein coding gene Chr5:21858362-21891219 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0029251
protein coding gene Chr5:22735919-22769235 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029154
protein coding gene Chr5:25337756-25371341 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029816
protein coding gene Chr5:22086485-22119379 (-)
PWK/PhJ MGP_PWKPhJ_G0028185
protein coding gene Chr5:20940837-20973649 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028016
protein coding gene Chr5:21430085-21464491 (-)
WSB/EiJ MGP_WSBEiJ_G0028541
protein coding gene Chr5:22155947-22189198 (-)



Homology
more
  • Human Ortholog
    SMARCD3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SMARCD3, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAF60C, CRACD3, Rsc6p
  • Links
    NCBI Gene ID: 6604
    neXtProt AC: NX_Q6STE5
    UniProt: Q6STE5

  • Chr Location
    7q36.1; chr7:151238973-151277436 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66993 NCBI Gene Model | MGI Sequence Detail 31835 C57BL/6J ±  kb
transcript NM_025891 RefSeq | MGI Sequence Detail 1743 C57BL/6  
polypeptide Q6P9Z1 UniProt | EBI | MGI Sequence Detail 483 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015267 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
  • InterPro Domains
    IPR019835 SWIB domain
    IPR003121 SWIB/MDM2 domain
    IPR036885 SWIB/MDM2 domain superfamily
    IPR038043 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1925633
References
more
  • Summaries
    All 64
    Developmental Gene Expression 22
    Diseases 1
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:257963 Sun X, et al., Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function. Biol Open. 2018 Jan 5;7(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory