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Ormdl2 Gene Detail
Summary
  • Symbol
    Ormdl2
  • Name
    ORM1-like 2 (S. cerevisiae)
  • Synonyms
    0610012C09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914094
    NCBI Gene: 66844
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128817902-128821645 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 77.16 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914094
protein coding gene Chr10:128817457-128821645 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017885
protein coding gene Chr10:132611765-132615934 (-)
A/J MGP_AJ_G0017860
protein coding gene Chr10:127273615-127278396 (-)
AKR/J MGP_AKRJ_G0017823
protein coding gene Chr10:130989218-130993372 (-)
BALB/cJ MGP_BALBcJ_G0017824
protein coding gene Chr10:127635120-127639312 (-)
C3H/HeJ MGP_C3HHeJ_G0017647
protein coding gene Chr10:131160527-131164680 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018279
protein coding gene Chr10:137078537-137082732 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015957
protein coding gene Chr10:121184830-121188512 (-)
CAST/EiJ MGP_CASTEiJ_G0017208
protein coding gene Chr10:131883518-131887671 (-)
CBA/J MGP_CBAJ_G0017617
protein coding gene Chr10:142672907-142677061 (-)
DBA/2J MGP_DBA2J_G0017723
protein coding gene Chr10:126328787-126332966 (-)
FVB/NJ MGP_FVBNJ_G0017718
protein coding gene Chr10:125252420-125256622 (-)
LP/J MGP_LPJ_G0017797
protein coding gene Chr10:133184438-133188604 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017746
protein coding gene Chr10:145230422-145245168 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018319
protein coding gene Chr10:131096443-131100640 (-)
PWK/PhJ MGP_PWKPhJ_G0016993
protein coding gene Chr10:126598347-126602576 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016782
protein coding gene Chr10:130203106-130208094 (-)
WSB/EiJ MGP_WSBEiJ_G0017267
protein coding gene Chr10:131321679-131325830 (-)



Homology
more
  • Human Ortholog
    ORMDL2, ORMDL sphingolipid biosynthesis regulator 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ORMDL2, ORMDL sphingolipid biosynthesis regulator 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    adoplin-2, HSPC160, MST095, MSTP095
  • Links
    NCBI Gene ID: 29095
    neXtProt AC: NX_Q53FV1
    UniProt: Q53FV1

  • Chr Location
    12q13.2; chr12:55818022-55821175 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025353 Ensembl Gene Model | MGI Sequence Detail 3744 C57BL/6J ±  kb
transcript ENSMUST00000219524 Ensembl | MGI Sequence Detail 724 Not Applicable  
polypeptide ENSMUSP00000151697 Ensembl | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:221146 Siow D, et al., ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. J Lipid Res. 2015 Apr;56(4):898-908

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory