Ormdl2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ormdl2
ORM1-like 2 (S. cerevisiae)
MGI:1914094

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Ormdl1^em1Pdra/\Ormdl1^em1Pdra \Ormdl2^em1Pdra/\Ormdl2^em1Pdra C57BL/6-Ormdl1^em1Pdra Ormdl2^em1Pdra	normal immune system phenotype	J:349248
\Ormdl1^em1Pdra/\Ormdl1^em1Pdra \Ormdl2^em1Pdra/\Ormdl2^em1Pdra \Ormdl3^em1Pdra/\Ormdl3^em1Pdra C57BL/6-Ormdl1^em1Pdra Ormdl2^em1Pdra Ormdl3^em1Pdra	prenatal lethality, complete penetrance	J:349248
\Ormdl2^em1Pdra/\Ormdl2^em1Pdra \Ormdl3^em1Pdra/\Ormdl3^em1Pdra C57BL/6-Ormdl2^em1Pdra Ormdl3^em1Pdra	abnormal mast cell physiology	J:328837
	abnormal type I hypersensitivity reaction	J:328837
	increased ceramide level	J:328837
	increased interleukin-4 secretion	J:328837
	increased interleukin-6 secretion	J:328837
	increased mast cell degranulation	J:328837
	increased sphingosine level	J:328837
	increased tumor necrosis factor secretion	J:328837

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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