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Fam210a Gene Detail
Summary
  • Symbol
    Fam210a
  • Name
    family with sequence similarity 210, member A
  • Synonyms
    4933403F05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914000
    NCBI Gene: 108654
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:68260187-68300333 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 40.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    212 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914000
protein coding gene Chr18:68260175-68300333 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024533
protein coding gene Chr18:68606088-68647603 (-)
A/J MGP_AJ_G0024500
protein coding gene Chr18:65625101-65665578 (-)
AKR/J MGP_AKRJ_G0024471
protein coding gene Chr18:67540603-67580992 (-)
BALB/cJ MGP_BALBcJ_G0024500
protein coding gene Chr18:65788713-65830109 (-)
C3H/HeJ MGP_C3HHeJ_G0024268
protein coding gene Chr18:67679166-67720291 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024946
protein coding gene Chr18:70396441-70439616 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022377
protein coding gene Chr18:64977654-65020361 (-)
CAST/EiJ MGP_CASTEiJ_G0023741
protein coding gene Chr18:67716857-67761956 (-)
CBA/J MGP_CBAJ_G0024237
protein coding gene Chr18:72823744-72863899 (-)
DBA/2J MGP_DBA2J_G0024367
protein coding gene Chr18:65247358-65287961 (-)
FVB/NJ MGP_FVBNJ_G0024333
protein coding gene Chr18:64622503-64662689 (-)
LP/J MGP_LPJ_G0024451
protein coding gene Chr18:68465706-68505825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024363
protein coding gene Chr18:74076004-74135417 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024994
protein coding gene Chr18:67705068-67745188 (-)
PWK/PhJ MGP_PWKPhJ_G0023485
protein coding gene Chr18:65559252-65604548 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023289
protein coding gene Chr18:67865249-67906609 (-)
WSB/EiJ MGP_WSBEiJ_G0023804
protein coding gene Chr18:67621444-67662010 (-)



Homology
more
  • Human Ortholog
    FAM210A, family with sequence similarity 210 member A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FAM210A, family with sequence similarity 210 member A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C18orf19, HsT2329
  • Links
    NCBI Gene ID: 125228
    neXtProt AC: NX_Q96ND0
    UniProt: Q96ND0

  • Chr Location
    18p11.21; chr18:13663347-13726592 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 2 alleles in 4 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit embryonic lethality after E9.5. Mice heterozygous for this allele exhibit decreased bone strength, compact bone thickness, compact bone volume, bone mineral density and bone ossification with increased osteoclasts.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038121 Ensembl Gene Model | MGI Sequence Detail 40147 C57BL/6J ±  kb
transcript ENSMUST00000042852 Ensembl | MGI Sequence Detail 9651 Not Applicable  
polypeptide ENSMUSP00000045927 Ensembl | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 95

    Microarray probesets 9
Other
Accession IDs
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MGI:2147190, MGI:2147365, MGI:3034565
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:261817 Tanaka KI, et al., FAM210A is a novel determinant of bone and muscle structure and strength. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3759-E3768

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory