Mims1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mims1
mitochondrial inner membrane scaffold 1
MGI:1914000

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mims1^{tm1b(EUCOMM)Wtsi}/Mims1⁺ involves: BALB/cJ * C57BL/6N	abnormal compact bone morphology	J:261817
	decreased bone mineral density	J:261817
	decreased bone ossification	J:261817
	decreased bone strength	J:261817
	decreased compact bone thickness	J:261817
	decreased compact bone volume	J:261817
	increased osteoclast cell number	J:261817
Mims1^{tm1b(EUCOMM)Wtsi}/Mims1^{tm1b(EUCOMM)Wtsi} involves: BALB/cJ * C57BL/6N	embryonic lethality during organogenesis, complete penetrance	J:261817
Mims1^{tm1c(EUCOMM)Wtsi}/Mims1^{tm1c(EUCOMM)Wtsi} Tg(ACTA1-cre/Esr1)2Kesr/0 involves: C3H C57BL/6N * SJL	abnormal limb morphology	J:261817
	decreased bone mineral density	J:261817
	decreased grip strength	J:261817
	normal growth/size/body region phenotype	J:261817
	increased osteoclast cell number	J:261817
Mims1^{tm1c(EUCOMM)Wtsi}/Mims1^{tm1c(EUCOMM)Wtsi} Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6N CBA * SJL	abnormal limb morphology	J:261817
	decreased body weight	J:261817
	decreased bone mineral content	J:261817
	decreased bone mineral density	J:261817
	decreased bone ossification	J:261817
	decreased bone strength	J:261817
	decreased bone trabecula number	J:261817
	decreased compact bone thickness	J:261817
	decreased compact bone volume	J:261817
	decreased grip strength	J:261817
	decreased trabecular bone volume	J:261817
	normal homeostasis/metabolism phenotype	J:261817
	increased bone trabecular spacing	J:261817
	increased osteoclast cell number	J:261817
	premature death	J:261817

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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