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Bccip Gene Detail
Summary
  • Symbol
    Bccip
  • Name
    BRCA2 and CDKN1A interacting protein
  • Synonyms
    1110013J05Rik, TOK-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913415
    NCBI Gene: 66165
  • Gene Overview
    MyGene.info: BCCIP
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:133709333-133721145 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 77.30 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913415
protein coding gene Chr7:133709333-133721145 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033124
protein coding gene Chr7:138466956-138479246 (+)
A/J MGP_AJ_G0033106
protein coding gene Chr7:134628729-134640863 (+)
AKR/J MGP_AKRJ_G0033038
protein coding gene Chr7:138234603-138245858 (+)
BALB/cJ MGP_BALBcJ_G0033107
protein coding gene Chr7:134339756-134351004 (+)
C3H/HeJ MGP_C3HHeJ_G0032821
protein coding gene Chr7:138070547-138081826 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033618
protein coding gene Chr7:143719946-143733731 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030589
protein coding gene Chr7:135898839-135910477 (+)
CAST/EiJ MGP_CASTEiJ_G0032151
protein coding gene Chr7:129982543-129993697 (+)
CBA/J MGP_CBAJ_G0032794
protein coding gene Chr7:148581476-148592769 (+)
DBA/2J MGP_DBA2J_G0032946
protein coding gene Chr7:132645697-132657166 (+)
FVB/NJ MGP_FVBNJ_G0032899
protein coding gene Chr7:132487730-132498938 (+)
LP/J MGP_LPJ_G0033040
protein coding gene Chr7:139985172-139997861 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032931
protein coding gene Chr7:149477173-149488608 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033638
protein coding gene Chr7:137241486-137253751 (+)
PWK/PhJ MGP_PWKPhJ_G0031857
protein coding gene Chr7:125666119-125677427 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031703
protein coding gene Chr7:124016476-124027637 (+)
WSB/EiJ MGP_WSBEiJ_G0032262
protein coding gene Chr7:138120123-138132745 (+)



Homology
more
  • Human Ortholog
    BCCIP, BRCA2 and CDKN1A interacting protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BCCIP, BRCA2 and CDKN1A interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TOK1, TOK-1
  • Links
    NCBI Gene ID: 56647
    neXtProt AC: NX_Q9P287
    UniProt: Q9P287

  • Chr Location
    10q26.2; chr10:125823535-125853695 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41629
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BCCIP
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66165 NCBI Gene Model | MGI Sequence Detail 11813 C57BL/6J ±  kb
transcript NM_025392 RefSeq | MGI Sequence Detail 1260 C57BL/6  
polypeptide Q9CWI3 UniProt | EBI | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 96
    cDNA 96

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:240998 Huhn SC, et al., Regulation of spindle integrity and mitotic fidelity by BCCIP. Oncogene. 2017 Aug 17;36(33):4750-4766

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory