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Smpx
Gene Detail
Symbol

Name
ID
Smpx
small muscle protein, X-linked
MGI:1913356
Synonyms
1010001C09Rik, chisel, Csl
Feature Type
protein coding gene
Genetic Map
Chromosome X
72.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:157698910-157752591 bp, + strand
From VEGA annotation of GRCm38

  53682 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8640  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SMPX
Gene Tree: Smpx

Human
homologs
SMPX, small muscle protein, X-linked
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23676
neXtProt AC: NX_Q9UHP9

Human Synonyms: DFN6, DFNX4

Human Chr (Location): Xp22.1; chrX:21705972-21758160 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SMPX

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
 
Mice homozygous for a null mutation do not exhibit defects in heart or skeletal muscle morphology or development.
 
Interactions
Smpx interacts with 83 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component contractile fiber, costamere, ...
External Resources: FuncBase
Expression
Literature Summary: (30 records)
Data Summary: Results (256)    Tissues (120)    Images (45)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 254
RT-PCR 2
cDNA source data(45)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase smpx ; ZFIN smpx    NEW 
Molecular
reagents
All nucleic(48) cDNA(45) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000019394 (Evidence)
Ensembl Gene Model ENSMUSG00000041476 (Evidence)
Entrez Gene 66106 (Evidence)
UniGene 140340
DFCI TC1596183, TC1579941
DoTS DT.94398543, DT.533085, DT.97397462, DT.94398544
NIA Mouse Gene Index U020356
Consensus CDS Project CCDS41190.1
International Mouse Phenotyping Consortium Status Smpx
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019394 VEGA Gene Model | MGI Sequence Detail 53682 C57BL/6J ±  kb
transcript OTTMUST00000046285 VEGA | MGI Sequence Detail 898 Not Applicable 
polypeptide OTTMUSP00000020907 VEGA | MGI Sequence Detail 85 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(7) UniProt(3)
Polymorphisms
SNPs within 2kb(266 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015298 small muscular protein
References
(Earliest) J:69167 Patzak D, et al., Identification, mapping, and genomic structure of a novel X-chromosomal human gene (SMPX) encoding a small muscular protein. Hum Genet. 1999 Nov;105(5):506-12
(Latest) J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
All references(54)
Other
accession IDs
MGI:1927114

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory