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Abhd6
Gene Detail
 Symbol
Name
ID
Abhd6
abhydrolase domain containing 6
MGI:1913332
Synonyms 0610041D24Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
4.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:8002902-8056555 bp, + strand
From NCBI annotation of GRCm38

  53654 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23246  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Abhd6

Human
homologs
Human Homolog ABHD6, abhydrolase domain containing 6
NCBI Gene ID 57406
neXtProt AC  NX_Q9BV23
Human Chr (Location)  3p14.3; chr3:58237506-58294738 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(15) Targeted(2)
Interactions
Abhd6 interacts with 153 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process long term synaptic depression, negative regulation of cell migration, ...
Component alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, extracellular vesicular exosome, ...
Function acylglycerol lipase activity, catalytic activity, ...
External Resources: FuncBase
Expression
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(46) cDNA(46)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000025277 (Evidence)
Entrez Gene66082 (Evidence)
UniGene181473
DFCITC1579365, TC1692211
DoTSDT.101274719, DT.101290671, DT.101368663, DT.110761857, DT.110896140, DT.55100649, DT.94230907
EC3.1.1.23
Consensus CDS ProjectCCDS26808.1
International Mouse Knockout Project StatusAbhd6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 66082 NCBI Gene Model | MGI Sequence Detail 53654 C57BL/6J ±  kb
transcript NM_025341 RefSeq | MGI Sequence Detail 2018 C57BL/6 
polypeptide Q8R2Y0 UniProt | EBI | MGI Sequence Detail 336 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(273 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000073 Alpha/beta hydrolase fold-1
InterPro IPR000639 Epoxide hydrolase-like
Protein Ontology PR:000030516 monoacylglycerol lipase ABHD6
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203779 Thomas G, et al., The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome. Cell Rep. 2013 Oct 31;5(2):508-20
All references(37)
Other
accession IDs
MGI:2138123, MGI:2145774

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory