Abhd6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abhd6
abhydrolase domain containing 6
MGI:1913332

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abhd6^{tm1a(EUCOMM)Hmgu}/Abhd6⁺ C57BL/6N-Abhd6^{tm1a(EUCOMM)Hmgu}	increased insulin secretion	J:215257
Abhd6^{tm1a(EUCOMM)Hmgu}/Abhd6^{tm1a(EUCOMM)Hmgu} C57BL/6N-Abhd6^{tm1a(EUCOMM)Hmgu}	abnormal adipose tissue morphology	J:234876
	abnormal body temperature homeostasis	J:234876
	abnormal enzyme/coenzyme activity	J:234876
	abnormal lipid level	J:215257
	abnormal liver morphology	J:234876
	abnormal pancreatic beta cell physiology	J:215257
	browned white adipose tissue morphology	J:234876
	decreased body fat mass	J:234876
	decreased body weight	J:234876
	decreased brown fat cell size	J:234876
	decreased circulating insulin level	J:234876
	decreased food intake	J:234876
	decreased insulin secretion	J:234876
	decreased liver triglyceride level	J:234876
	decreased liver weight	J:234876
	decreased susceptibility to diet-induced obesity	J:234876
	decreased white fat cell size	J:234876
	improved glucose tolerance	J:234876
	increased adipocyte glucose uptake	J:234876
	increased circulating insulin level	J:215257
	increased energy expenditure	J:234876
	increased fatty acid beta-oxidation	J:234876
	increased insulin secretion	J:215257, J:234876
	increased insulin sensitivity	J:234876
	increased locomotor activity	J:234876
	increased muscle cell glucose uptake	J:234876
	increased oxygen consumption	J:234876
Abhd6^{tm1c(EUCOMM)Hmgu}/Abhd6^{tm1c(EUCOMM)Hmgu} Tg(Ins1-cre/ERT)1Lphi/0 involves: C57BL/6N * CD-1	improved glucose tolerance	J:215257
	increased circulating insulin level	J:215257
	increased insulin secretion	J:215257

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23