Abhd6^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Abhd6^em1(IMPC)Mbp
• Name: abhydrolase domain containing 6; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6140124
• Gene: Abhd6 Location: Chr14:14413010-14466871 bp, - strand Genetic Position: Chr14, 4.69 cM
• Alliance: Abhd6^em1(IMPC)Mbp page
• IMPC: Abhd6 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences GAACAAACGACAGTAGGCAG, GGAGGGTAAAGGACAAGAGC, GTGTGGATATTTTTAGGCAG, and TGGGAATGTCATCATGAGAC. This resulted in deletion(s) of 2 bp (location: Chr14:14430188-14430189; GRCm39), 2 bp (location: Chr14:14430203-14430204; GRCm39), and 14 bp (location: Chr14:14430318-14430331; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abhd6 Mutation: 37 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)