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Plag1
Gene Detail
 Symbol
Name
ID
Plag1
pleiomorphic adenoma gene 1
MGI:1891916
Feature Type protein coding gene
Genetic Map
Chromosome 4
2.18 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:3900996-3938423 bp, - strand
From VEGA annotation of GRCm38

  37428 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1993  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Plag1

Human
homologs
Human Homolog PLAG1, pleiomorphic adenoma gene 1
NCBI Gene ID 5324
neXtProt AC  NX_Q6DJT9
Human Synonyms  PSA, SGPA, ZNF912
Human Chr (Location)  8q12; chr8:56160904-56211300 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PLAG1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display reduced male fertility, small seminal vesicles and ventral prostate, reduced litter size (females only), reduced embryonic and postnatal growth, and delayed eyelid opening.
 
Interactions
Plag1 interacts with 365 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process gland morphogenesis, multicellular organism growth, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (251)    Tissues (192)    Images (35)
Theiler Stages: 2, 3, 4, 5, 15, 17, 18, 20, 21, 22, 23, 28
Assay TypeResults
RNA in situ 238
RT-PCR 13
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(10) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004402 (Evidence)
Ensembl Gene ModelENSMUSG00000003282 (Evidence)
Entrez Gene56711 (Evidence)
UniGene331467
DFCITC1593225, TC1613152, TC1624144, TC1678206
DoTSDT.110782685, DT.91567825, DT.94165428, DT.97346087
NIA Mouse Gene IndexU024808
Consensus CDS ProjectCCDS17941.1
International Mouse Knockout Project StatusPlag1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004402 VEGA Gene Model | MGI Sequence Detail 37428 C57BL/6J ±  kb
transcript OTTMUST00000009975 VEGA | MGI Sequence Detail 4774 Not Applicable 
polypeptide OTTMUSP00000004778 VEGA | MGI Sequence Detail 499 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(18) UniProt(2)
Polymorphisms SNPs within 2kb(174 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000012822 zinc finger protein PLAG1
References (Earliest) J:64937 Kas K, et al., Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations [published erratum appears in Nat Genet 1997 Apr;15(4):411]. Nat Genet. 1997 Feb;15(2):170-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory