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Lpin2
Gene Detail
Symbol

Name
ID
Lpin2
lipin 2
MGI:1891341
Synonyms
2610511G02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
41.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:71182560-71249817 bp, + strand
From VEGA annotation of GRCm38

  67258 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LPIN2
Gene Tree: Lpin2

Human
homologs
LPIN2, lipin 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9663
neXtProt AC: NX_Q92539

Human Chr (Location): 18p11.31; chr18:2916994-3013315 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human LPIN2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lpin2 interacts with 335 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process dephosphorylation, fatty acid catabolic process, ...
Component cytoplasm, cytosol, ...
Function hydrolase activity, phosphatidate phosphatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (20)    Tissues (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
cDNA source data(147)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase lpin2    NEW 
Molecular
reagents
All nucleic(150) cDNA(149) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000024753 (Evidence)
Ensembl Gene Model ENSMUSG00000024052 (Evidence)
Entrez Gene 64898 (Evidence)
UniGene 227924
DFCI TC1577310, TC1599612, TC1589698, TC1610344, TC1617301, TC1610963
DoTS DT.101208955, DT.101174051, DT.50315551, DT.97349798, DT.101387183, DT.101355362, DT.94261089, DT.55201229, DT.94183114, DT.94131942
EC 3.1.3.4
Consensus CDS Project CCDS28956.1, CCDS50177.1
International Mouse Phenotyping Consortium Status Lpin2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024753 VEGA Gene Model | MGI Sequence Detail 67258 C57BL/6J ±  kb
transcript OTTMUST00000060991 VEGA | MGI Sequence Detail 4167 Not Applicable 
polypeptide OTTMUSP00000029837 VEGA | MGI Sequence Detail 931 Not Applicable 

For the selected sequences
All sequences(97) RefSeq(12) UniProt(6)
Polymorphisms
SNPs within 2kb(248 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023214 HAD-like domain
InterPro IPR007651 Lipin, N-terminal
InterPro IPR013209 LNS2, Lipin/Ned1/Smp2
InterPro IPR026744 Phosphatidate phosphatase LPIN2
Protein Ontology PR:000009895 phosphatidate phosphatase LPIN2
References
(Earliest) J:65653 Wertz K, et al., Large-scale screen for genes involved in gonad development. Mech Dev. 2000 Nov;98(1-2):51-70
(Latest) J:220917 Csaki LS, et al., Lipin-1 and lipin-3 together determine adiposity in vivo. Mol Metab. 2014 Apr;3(2):145-54
All references(36)
Other
accession IDs
MGI:1915262, MGI:2146881, MGI:2147099

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory