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Lpin2
Gene Detail
 Symbol
Name
ID
Lpin2
lipin 2
MGI:1891341
Synonyms 2610511G02Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
41.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:71182560-71249817 bp, + strand
From VEGA annotation of GRCm38

  67258 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Lpin2

Human
homologs
Human Homolog LPIN2, lipin 2
NCBI Gene ID 9663
neXtProt AC  NX_Q92539
Human Chr (Location)  18p11.31; chr18:2916994-3013315 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LPIN2
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lpin2 interacts with 336 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process dephosphorylation, fatty acid metabolic process, ...
Component cytoplasm, cytosol, ...
Function hydrolase activity, phosphatidate phosphatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (20)    Tissues (17)   
Theiler Stages: 15, 19, 22, 24, 26, 27, 28
Assay TypeResults
RNA in situ 20
cDNA source data(147)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(150) cDNA(149) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000024753 (Evidence)
Ensembl Gene ModelENSMUSG00000024052 (Evidence)
Entrez Gene64898 (Evidence)
UniGene227924
DFCITC1577310, TC1589698, TC1599612, TC1610344, TC1610963, TC1617301
DoTSDT.101174051, DT.101208955, DT.101355362, DT.101387183, DT.50315551, DT.55201229, DT.94131942, DT.94183114, DT.94261089, DT.97349798
EC3.1.3.4
Consensus CDS ProjectCCDS28956.1, CCDS50177.1
International Mouse Knockout Project StatusLpin2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024753 VEGA Gene Model | MGI Sequence Detail 67258 C57BL/6J ±  kb
transcript OTTMUST00000060991 VEGA | MGI Sequence Detail 4167 Not Applicable 
polypeptide OTTMUSP00000029837 VEGA | MGI Sequence Detail 931 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(10) UniProt(6)
Polymorphisms SNPs within 2kb(248 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023214 HAD-like domain
InterPro IPR007651 Lipin, N-terminal
InterPro IPR013209 LNS2, Lipin/Ned1/Smp2
InterPro IPR026744 Phosphatidate phosphatase LPIN2
Protein Ontology PR:000009895 phosphatidate phosphatase LPIN2
References (Earliest) J:65653 Wertz K, et al., Large-scale screen for genes involved in gonad development. Mech Dev. 2000 Nov;98(1-2):51-70
(Latest) J:189894 Dwyer JR, et al., Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2486-95
All references(32)
Other
accession IDs
MGI:1915262, MGI:2146881, MGI:2147099

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory