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Lpin2
Gene Detail
Symbol

Name
ID
Lpin2
lipin 2
MGI:1891341
Synonyms
2610511G02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
41.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:71182560-71249817 bp, + strand
From VEGA annotation of GRCm38

  67258 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8769  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Lpin2

Human
homologs
Human Homolog LPIN2, lipin 2
NCBI Gene ID 9663
neXtProt AC  NX_Q92539
Human Chr (Location)  18p11.31; chr18:2916994-3013315 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LPIN2
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lpin2 interacts with 336 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process dephosphorylation, fatty acid metabolic process, ...
Component cytoplasm, cytosol, ...
Function hydrolase activity, phosphatidate phosphatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (20)    Tissues (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
cDNA source data(147)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(150) cDNA(149) Primer pair(1)
Microarray probesets(6)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024753 VEGA Gene Model | MGI Sequence Detail 67258 C57BL/6J ±  kb
transcript OTTMUST00000060991 VEGA | MGI Sequence Detail 4167 Not Applicable 
polypeptide OTTMUSP00000029837 VEGA | MGI Sequence Detail 931 Not Applicable 

For the selected sequences
All sequences(100) RefSeq(10) UniProt(11)
Polymorphisms
SNPs within 2kb(248 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023214 HAD-like domain
InterPro IPR007651 Lipin, N-terminal
InterPro IPR013209 LNS2, Lipin/Ned1/Smp2
InterPro IPR026744 Phosphatidate phosphatase LPIN2
Protein Ontology PR:000009895 phosphatidate phosphatase LPIN2
References
(Earliest) J:65653 Wertz K, et al., Large-scale screen for genes involved in gonad development. Mech Dev. 2000 Nov;98(1-2):51-70
(Latest) J:189894 Dwyer JR, et al., Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2486-95
All references(32)
Other
accession IDs
MGI:1915262, MGI:2146881, MGI:2147099

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory