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Abcg4
Gene Detail
Symbol

Name
ID
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
MGI:1890594
Synonyms
6430517O04Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM, cytoband A5.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:44273188-44288615 bp, - strand
From VEGA annotation of GRCm38

  15428 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75179  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Abcg4

Human
homologs
Human Homolog ABCG4, ATP-binding cassette, sub-family G (WHITE), member 4
NCBI Gene ID 64137
neXtProt AC  NX_Q9H172
Human Synonyms  WHITE2
Human Chr (Location)  11q23.3; chr11:119149040-119162666 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a report allele exhibit increased brain lathosterol levels.
 
Interactions
Abcg4 interacts with 245 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Function protein heterodimerization activity, protein homodimerization activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (333)    Tissues (130)    Images (58)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 313
RT-PCR 20
cDNA source data(39)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(40) cDNA(39) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000029282 (Evidence)
Ensembl Gene ModelENSMUSG00000032131 (Evidence)
Entrez Gene192663 (Evidence)
UniGene101876
DFCITC1627651, TC1581179, TC1607857
DoTSDT.101376426, DT.522458, DT.91574818, DT.101376425, DT.97397070
NIA Mouse Gene IndexU030765
Consensus CDS ProjectCCDS23101.1
International Mouse Knockout Project StatusAbcg4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029282 VEGA Gene Model | MGI Sequence Detail 15428 C57BL/6J ±  kb
transcript OTTMUST00000072560 VEGA | MGI Sequence Detail 3997 Not Applicable 
polypeptide OTTMUSP00000037389 VEGA | MGI Sequence Detail 646 Not Applicable 

For the selected sequences
All sequences(82) RefSeq(2) UniProt(22)
Polymorphisms
SNPs within 2kb(144 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR013525 ABC-2 type transporter
InterPro IPR017871 ABC transporter, conserved site
InterPro IPR003439 ABC transporter-like
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000003571 ATP-binding cassette sub-family G member 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:198517 Murphy AJ, et al., Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis. Nat Med. 2013 May;19(5):586-94
All references(38)
Other
accession IDs
MGI:1924137

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory