Elac2
Gene Detail

Symbol Name ID

Elac2 elaC homolog 2 (E. coli) MGI:1890496

Synonyms

1110017O07Rik, D11Wsu80e, tRNase Z(L)

Feature Type

protein coding gene

Genetic Map

Chromosome 11

40.42 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr11:64979038-65002069 bp, + strand From VEGA annotation of GRCm38   23032 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Elac2

Human homologs

Human Homolog		ELAC2, elaC homolog 2 (E. coli)
NCBI Gene ID		60528
neXtProt AC		NX_Q9BQ52
Human Synonyms		ELC2, HPC2
Human Chr (Location)		17p11.2; chr17:12894929-12921381 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ELAC2

Alleles and phenotypes

All alleles(8) : Targeted(2) Gene trapped(6)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	tRNA processing
Component	mitochondrion, nucleus
Function	endonuclease activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (2)   
Theiler Stages: 11

Assay Type	Results
RT-PCR	6

cDNA source data(79)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(80) cDNA(79) Primer pair(1)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000005902 (Evidence)
Ensembl Gene Model	ENSMUSG00000020549 (Evidence)
Entrez Gene	68626 (Evidence)
UniGene	157711
DFCI	TC1578085, TC1606460, TC1774455
DoTS	DT.101329534, DT.102551278, DT.532149, DT.91327641, DT.94122601
NIA Mouse Gene Index	U012760
EC	3.1.26.11
Consensus CDS Project	CCDS24841.1
International Mouse Knockout Project Status	Elac2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005902	VEGA Gene Model | MGI Sequence Detail	23032	C57BL/6J
transcript	OTTMUST00000013128	VEGA | MGI Sequence Detail	2771	Not Applicable
polypeptide	OTTMUSP00000006092	VEGA | MGI Sequence Detail	831	Not Applicable

All sequences(62) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(135 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001279	Beta-lactamase-like
Protein Ontology	PR:000007015	zinc phosphodiesterase ELAC protein 2

References

(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)

Other accession IDs

MGD-MRK-34044, MGI:106352, MGI:1915876