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Elac2 Gene Detail
Summary
  • Symbol
    Elac2
  • Name
    elaC ribonuclease Z 2
  • Synonyms
    1110017O07Rik, D11Wsu80e, tRNase Z(L)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890496
    NCBI Gene: 68626
  • Gene Overview
    MyGene.info: ELAC2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:64979038-65002069 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 40.42 cM, cytoband B3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890496
protein coding gene Chr11:64979030-65002076 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018473
protein coding gene Chr11:65165972-65189576 (+)
A/J MGP_AJ_G0018442
protein coding gene Chr11:62737054-62759427 (+)
AKR/J MGP_AKRJ_G0018411
protein coding gene Chr11:64641736-64663930 (+)
BALB/cJ MGP_BALBcJ_G0018413
protein coding gene Chr11:62994147-63016816 (+)
C3H/HeJ MGP_C3HHeJ_G0018226
protein coding gene Chr11:64611526-64635362 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018865
protein coding gene Chr11:67147937-67171430 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016509
protein coding gene Chr11:59754215-59776338 (+)
CAST/EiJ MGP_CASTEiJ_G0017782
protein coding gene Chr11:64812212-64859199 (+)
CBA/J MGP_CBAJ_G0018200
protein coding gene Chr11:70104560-70128285 (+)
DBA/2J MGP_DBA2J_G0018309
protein coding gene Chr11:62283138-62305483 (+)
FVB/NJ MGP_FVBNJ_G0018299
protein coding gene Chr11:61938033-61960415 (+)
LP/J MGP_LPJ_G0018381
protein coding gene Chr11:65707305-65729605 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018323
protein coding gene Chr11:70992041-71015856 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018906
protein coding gene Chr11:64838759-64864171 (+)
PWK/PhJ MGP_PWKPhJ_G0017556
protein coding gene Chr11:62885140-62932342 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017346
protein coding gene Chr11:64683538-64705694 (+)
WSB/EiJ MGP_WSBEiJ_G0017835
protein coding gene Chr11:64454278-64477680 (+)



Homology
more
  • Human Ortholog
    ELAC2, elaC ribonuclease Z 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ELAC2, elaC ribonuclease Z 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COXPD17, ELC2, HPC2
  • Links
    NCBI Gene ID: 60528
    neXtProt AC: NX_Q9BQ52
    UniProt: Q9BQ52

  • Chr Location
    17p12; chr17:12991612-13018064 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ELAC2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020549 Ensembl Gene Model | MGI Sequence Detail 23032 C57BL/6J ±  kb
transcript ENSMUST00000071891 Ensembl | MGI Sequence Detail 2771 Not Applicable  
polypeptide ENSMUSP00000071788 Ensembl | MGI Sequence Detail 831 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 81
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-34044, MGI:106352, MGI:1915876
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:213151 Bogenhagen DF, et al., Initial steps in RNA processing and ribosome assembly occur at mitochondrial DNA nucleoids. Cell Metab. 2014 Apr 1;19(4):618-29

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory