About   Help   FAQ
Elac2
Gene Detail
Symbol

Name
ID
Elac2
elaC homolog 2 (E. coli)
MGI:1890496
Synonyms
1110017O07Rik, D11Wsu80e, tRNase Z(L)
Feature Type
protein coding gene
Genetic Map
Chromosome 11
40.42 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr11:64979038-65002069 bp, + strand
From VEGA annotation of GRCm38

  23032 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ELAC2
Gene Tree: Elac2

Human
homologs
ELAC2, elaC ribonuclease Z 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 60528
neXtProt AC: NX_Q9BQ52

Human Synonyms: COXPD17, ELC2, HPC2

Human Chr (Location): 17p11.2; chr17:12991612-13018064 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human ELAC2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Elac2 interacts with 80 markers (Mir18b, Mir30c-1, Mir30c-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 6
cDNA source data(79)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase elac2 ; ZFIN elac2    NEW 
Molecular
reagents
All nucleic(80) cDNA(79) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000005902 (Evidence)
Ensembl Gene Model ENSMUSG00000020549 (Evidence)
Entrez Gene 68626 (Evidence)
UniGene 157711
DFCI TC1578085, TC1606460, TC1774455
DoTS DT.101329534, DT.102551278, DT.532149, DT.91327641, DT.94122601
NIA Mouse Gene Index U012760
EC 3.1.26.11
Consensus CDS Project CCDS24841.1
International Mouse Phenotyping Consortium Status Elac2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005902 VEGA Gene Model | MGI Sequence Detail 23032 C57BL/6J ±  kb
transcript OTTMUST00000013128 VEGA | MGI Sequence Detail 2771 Not Applicable 
polypeptide OTTMUSP00000006092 VEGA | MGI Sequence Detail 831 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(10) UniProt(4)
Polymorphisms
SNPs within 2kb(178 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001279 Beta-lactamase-like
Protein Ontology PR:000007015 zinc phosphodiesterase ELAC protein 2
References
(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:213151 Bogenhagen DF, et al., Initial steps in RNA processing and ribosome assembly occur at mitochondrial DNA nucleoids. Cell Metab. 2014 Apr 1;19(4):618-29
All references(42)
Other
accession IDs
MGD-MRK-34044, MGI:106352, MGI:1915876

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory