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Elac2
Gene Detail
Symbol

Name
ID
Elac2
elaC homolog 2 (E. coli)
MGI:1890496
Synonyms
1110017O07Rik, D11Wsu80e, tRNase Z(L)
Feature Type
protein coding gene
Genetic Map
Chromosome 11
40.42 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr11:64979038-65002069 bp, + strand
From VEGA annotation of GRCm38

  23032 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Elac2

Human
homologs
Human Homolog ELAC2, elaC ribonuclease Z 2
NCBI Gene ID 60528
neXtProt AC  NX_Q9BQ52
Human Synonyms  COXPD17, ELC2, HPC2
Human Chr (Location)  17p11.2; chr17:12991612-13018064 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human ELAC2
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Elac2 interacts with 80 markers (Mir18b, Mir30c-1, Mir30c-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process mitochondrial tRNA 3'-trailer cleavage, endonucleolytic, tRNA processing
Component mitochondrion, nucleoplasm, ...
Function endonuclease activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 6
cDNA source data(79)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(80) cDNA(79) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000005902 (Evidence)
Ensembl Gene ModelENSMUSG00000020549 (Evidence)
Entrez Gene68626 (Evidence)
UniGene157711
DFCITC1578085, TC1774455, TC1606460
DoTSDT.101329534, DT.91327641, DT.94122601, DT.532149, DT.102551278
NIA Mouse Gene IndexU012760
EC3.1.26.11
Consensus CDS ProjectCCDS24841.1
International Mouse Knockout Project StatusElac2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005902 VEGA Gene Model | MGI Sequence Detail 23032 C57BL/6J ±  kb
transcript OTTMUST00000013128 VEGA | MGI Sequence Detail 2771 Not Applicable 
polypeptide OTTMUSP00000006092 VEGA | MGI Sequence Detail 831 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(10) UniProt(7)
Polymorphisms
SNPs within 2kb(178 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001279 Beta-lactamase-like
Protein Ontology PR:000007015 zinc phosphodiesterase ELAC protein 2
References
(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)
Other
accession IDs
MGD-MRK-34044, MGI:106352, MGI:1915876

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory