Elac2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elac2
elaC ribonuclease Z 2
MGI:1890496

22 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elac2^em1Afi/Elac2^em1Afi C57BL/6N-Elac2^em1Afi	abnormal prostate gland anterior lobe morphology	J:336403
	abnormal prostate gland dorsolateral lobe morphology	J:336403
	normal mortality/aging	J:336403
	prostate gland anterior lobe hyperplasia	J:336403
	prostate gland dorsolateral lobe hyperplasia	J:336403
	prostate gland hyperplasia	J:336403
	prostate gland inflammation	J:336403
	normal reproductive system phenotype	J:336403
Elac2^{tm1b(EUCOMM)Wtsi}/Elac2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Elac2^{tm1b(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Elac2^{tm1c(EUCOMM)Wtsi}/Elac2^{tm1c(EUCOMM)Wtsi} Tg(Ckmm-cre)5Khn/0 involves: C57BL/6N * FVB	abnormal cell physiology	J:265839
	abnormal heart echocardiography feature	J:265839
	abnormal mitochondrial ATP synthesis coupled electron transport	J:265839
	abnormal mitochondrial physiology	J:265839
	abnormal oxidative phosphorylation	J:265839
	abnormal translation	J:265839
	normal cellular phenotype	J:265839
	decreased body weight	J:265839
	decreased cardiac muscle contractility	J:265839
	dilated cardiomyopathy	J:265839
	increased heart weight	J:265839
	premature death	J:265839
Elac2^{tm1d(EUCOMM)Wtsi}/Elac2^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality, complete penetrance	J:265839

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23