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Dach2 Gene Detail
Summary
  • Symbol
    Dach2
  • Name
    dachshund family transcription factor 2
  • Synonyms
    9430028N04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890446
    NCBI Gene: 93837
  • Gene Overview
    MyGene.info: DACH2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:113297510-113836386 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 49.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3070 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890446
protein coding gene ChrX:113297510-113836386 (.)
129S1/SvImJ MGP_129S1SvImJ_G0036037
protein coding gene ChrX:110056297-110602988 (+)
A/J MGP_AJ_G0036017
protein coding gene ChrX:109864560-110421411 (+)
AKR/J MGP_AKRJ_G0035936
protein coding gene ChrX:113322096-113902473 (+)
BALB/cJ MGP_BALBcJ_G0036009
protein coding gene ChrX:108477004-109002167 (+)
C3H/HeJ MGP_C3HHeJ_G0035714
protein coding gene ChrX:110468059-111019462 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036533
protein coding gene ChrX:113287760-113860605 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033360
protein coding gene ChrX:106517682-107007848 (+)
CAST/EiJ MGP_CASTEiJ_G0035001
protein coding gene ChrX:94348878-94895074 (+)
CBA/J MGP_CBAJ_G0035690
protein coding gene ChrX:116831386-117416157 (+)
DBA/2J MGP_DBA2J_G0035843
protein coding gene ChrX:109062255-109597137 (+)
FVB/NJ MGP_FVBNJ_G0035784
protein coding gene ChrX:108482825-109016523 (+)
LP/J MGP_LPJ_G0035936
protein coding gene ChrX:110936246-111484198 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035814
protein coding gene ChrX:122273473-122941606 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036560
protein coding gene ChrX:109581740-110151938 (+)
PWK/PhJ MGP_PWKPhJ_G0034695
protein coding gene ChrX:91823908-92342088 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034526
protein coding gene ChrX:95182075-95725508 (+)
WSB/EiJ MGP_WSBEiJ_G0035138
protein coding gene ChrX:108391792-108968946 (+)



Homology
more
  • Human Ortholog
    DACH2, dachshund family transcription factor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DACH2, dachshund family transcription factor 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 117154
    neXtProt AC: NX_Q96NX9
    UniProt: Q96NX9

  • Chr Location
    Xq21.2; chrX:86148451-86832602 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Targeted disruption of this gene results in homozygous females and hemizygous males that are viable, fertile and do not display gross defects in eye development or brain function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 93837 NCBI Gene Model | MGI Sequence Detail 538877 C57BL/6J ±  kb
transcript NM_001142570 RefSeq | MGI Sequence Detail 5991 C57BL/6  
polypeptide Q925Q8 UniProt | EBI | MGI Sequence Detail 634 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1924585
References
more
  • Summaries
    All 31
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227705 Macpherson PC, et al., Dach2-Hdac9 signaling regulates reinnervation of muscle endplates. Development. 2015 Dec 1;142(23):4038-48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory