About   Help   FAQ
Paxip1
Gene Detail
Symbol

Name
ID
Paxip1
PAX interacting (with transcription-activation domain) protein 1
MGI:1890430
Synonyms
D5Ertd149e, PTIP
Feature Type
protein coding gene
Genetic Map
Chromosome 5
13.23 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:27740667-27791339 bp, - strand
From Ensembl annotation of GRCm38

  50673 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Paxip1
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Chemically induced (ENU)(2) Gene trapped(9) Radiation induced(3) Targeted(3)
Genomic Mutations involving Paxip1 (3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are developmentally retarded and embyronic lethal by E9.5.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Paxip1 interacts with 283 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process adipose tissue development, cellular response to DNA damage stimulus, ...
Component histone methyltransferase complex, nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (99)    Tissues (99)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 99
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(8) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000002221 (Evidence)
Entrez Gene55982 (Evidence)
DFCITC1575974, TC1643693, TC1637302
DoTSDT.91371200, DT.101384522, DT.531115, DT.94343547, DT.110648801
NIA Mouse Gene IndexU026024, U359103
Consensus CDS ProjectCCDS39039.1
International Mouse Knockout Project StatusPaxip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002221 Ensembl Gene Model | MGI Sequence Detail 50673 C57BL/6J ±  kb
transcript ENSMUST00000002291 Ensembl | MGI Sequence Detail 5052 Not Applicable 
polypeptide ENSMUSP00000002291 Ensembl | MGI Sequence Detail 1056 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(16) UniProt(1)
Polymorphisms
SNPs within 2kb(250 from dbSNP Build 137)    SNPs within 2kb including multiple locations(252)
Protein-related
information
ResourceIDDescription
InterPro IPR001357 BRCT domain
Protein Ontology PR:000012322 PAX-interacting protein 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:198413 Callen E, et al., 53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions. Cell. 2013 Jun 6;153(6):1266-80
All references(55)
Other
accession IDs
MGI:1098588

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory