Paxip1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Paxip1
PAX interacting (with transcription-activation domain) protein 1
MGI:1890430

35 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Paxip1^L5Jcs4/Paxip1^L5Jcs4 involves: C57BL/6	abnormal aortic arch development	J:140559
	abnormal placenta vasculature	J:140559
	abnormal vasculogenesis	J:140559
	abnormal vitelline vasculature morphology	J:140559
	decreased embryo size	J:140559
	distended pericardium	J:140559
	embryonic lethality during organogenesis, complete penetrance	J:140559
	embryonic lethality, complete penetrance	J:100332
	pale yolk sac	J:140559
	placental labyrinth hypoplasia	J:140559
Paxip1^L5Jcs36/Paxip1^L5Jcs36 involves: C57BL/6	abnormal allantois morphology	J:140559
	absent organized vascular network	J:140559
	caudal body truncation	J:140559
	decreased embryo size	J:140559
	embryonic growth retardation	J:140559
	embryonic lethality between implantation and somite formation, complete penetrance	J:100332
	embryonic lethality during organogenesis, complete penetrance	J:140559
	failure of chorioallantoic fusion	J:140559
	failure of heart looping	J:140559
	incomplete embryo turning	J:140559
	pallor	J:140559
Paxip1^tm1Gdr/Paxip1^tm1Gdr involves: 129S1/Sv * 129X1/SvJ	embryonic growth retardation	J:140559
Paxip1^tm1Gdr/Paxip1^tm1Gdr involves: 129S1/Sv * 129X1/SvJ	embryonic lethality, complete penetrance	J:140559
Paxip1^tm1Gdr/Paxip1^tm1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal allantois morphology	J:82319
	abnormal developmental patterning	J:82319
	abnormal DNA repair	J:82319
	abnormal egg cylinder morphology	J:82319
	abnormal heart development	J:82319
	abnormal mitosis	J:82319
	abnormal vitelline vasculature morphology	J:82319
	absent amnion	J:82319
	decreased cell proliferation	J:82319
	decreased DNA replication	J:82319
	decreased embryo size	J:82319
	decreased inner cell mass proliferation	J:82319
	disorganized embryonic tissue	J:82319
	embryonic growth arrest	J:82319
	embryonic lethality, complete penetrance	J:82319
	incomplete somite formation	J:82319
	increased cellular sensitivity to ionizing radiation	J:82319
	increased embryonic tissue cell apoptosis	J:82319
Paxip1^tm2Gdr/Paxip1^tm2Gdr involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:128440
Paxip1^tm2Gdr/Paxip1^tm2Gdr Tg(Nes-cre)1Atp/? involves: 129S1/Sv * 129X1/SvJ * FVB/N	neonatal lethality, complete penetrance	J:128440

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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