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Igf2bp2 Gene Detail
Summary
  • Symbol
    Igf2bp2
  • Name
    insulin-like growth factor 2 mRNA binding protein 2
  • Synonyms
    C330012H03Rik, IMP2, IMP-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890358
    NCBI Gene: 319765
  • Gene Overview
    MyGene.info: IGF2BP2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:22059009-22163299 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 13.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    348 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890358
protein coding gene Chr16:22059009-22163299 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022666
protein coding gene Chr16:19527700-19642027 (-)
A/J MGP_AJ_G0022628
protein coding gene Chr16:18582596-18689086 (-)
AKR/J MGP_AKRJ_G0022603
protein coding gene Chr16:19356395-19465942 (-)
BALB/cJ MGP_BALBcJ_G0022632
protein coding gene Chr16:18782603-18887476 (-)
C3H/HeJ MGP_C3HHeJ_G0022397
protein coding gene Chr16:19469416-19585707 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023083
protein coding gene Chr16:19950356-20065127 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020601
protein coding gene Chr16:19285917-19390234 (-)
CAST/EiJ MGP_CASTEiJ_G0021927
protein coding gene Chr16:19448083-19561213 (-)
CBA/J MGP_CBAJ_G0022369
protein coding gene Chr16:20775695-20899444 (-)
DBA/2J MGP_DBA2J_G0022501
protein coding gene Chr16:18565244-18670315 (-)
FVB/NJ MGP_FVBNJ_G0022476
protein coding gene Chr16:18536449-18640489 (-)
LP/J MGP_LPJ_G0022568
protein coding gene Chr16:19272992-19387425 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022496
protein coding gene Chr16:20353059-20465486 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023094
protein coding gene Chr16:19309741-19419081 (-)
PWK/PhJ MGP_PWKPhJ_G0021667
protein coding gene Chr16:18795449-18904958 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021497
protein coding gene Chr16:19087668-19205359 (-)
WSB/EiJ MGP_WSBEiJ_G0021970
protein coding gene Chr16:19271406-19382649 (-)



Homology
more
  • Human Ortholog
    IGF2BP2, insulin like growth factor 2 mRNA binding protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IGF2BP2, insulin like growth factor 2 mRNA binding protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IMP2, IMP-2, VICKZ2
  • Links
    NCBI Gene ID: 10644
    neXtProt AC: NX_Q9Y6M1
    UniProt: Q9Y6M1

  • Chr Location
    3q27.2; chr3:185643739-185825051 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human IGF2BP2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319765 NCBI Gene Model | MGI Sequence Detail 104291 C57BL/6J ±  kb
transcript NM_183029 RefSeq | MGI Sequence Detail 3902 C57BL/6  
polypeptide Q5SF07 UniProt | EBI | MGI Sequence Detail 592 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 136
    cDNA 134
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2442686
References
more
  • Summaries
    All 47
    Developmental Gene Expression 11
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:52252 Nielsen J, et al., A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol. 1999 Feb;19(2):1262-70
  • Latest
    J:246575 Zhou X, et al., HMGB2 regulates satellite-cell-mediated skeletal muscle regeneration through IGF2BP2. J Cell Sci. 2016 Nov 15;129(22):4305-4316

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory