Igf2bp2
Gene Detail

Symbol Name ID

Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 MGI:1890358

Synonyms

C330012H03Rik, IMP-2

Feature Type

protein coding gene

Genetic Map

Chromosome 16

13.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr16:22059009-22163299 bp, - strand From VEGA annotation of GRCm38   104291 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4774  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Igf2bp2

Human homologs

Human Homolog		IGF2BP2, insulin-like growth factor 2 mRNA binding protein 2
NCBI Gene ID		10644
neXtProt AC		NX_Q9Y6M1
Human Synonyms		IMP2, IMP-2, p62, VICKZ2
Human Chr (Location)		3q27.2; chr3:185361527-185542827 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human IGF2BP2

Alleles and phenotypes

All alleles(78) : Targeted(4) Gene trapped(74)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	regulation of translation
Component	cytoplasm, cytoskeleton, ...
Function	mRNA 3'-UTR binding, mRNA 5'-UTR binding, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (9)    Tissues (5)    Images (1)
Theiler Stages: 17, 20, 21, 28

Assay Type	Results
RNA in situ	2
Northern blot	5
RT-PCR	2

cDNA source data(129)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(131) cDNA(129) Primer pair(1) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000025859 (Evidence)
Ensembl Gene Model	ENSMUSG00000033581 (Evidence)
Entrez Gene	319765 (Evidence)
UniGene	294740
DFCI	TC1597206, TC1606484, TC1646630, TC1777028
DoTS	DT.101177634, DT.101380942, DT.101380948, DT.101737824, DT.492410
NIA Mouse Gene Index	U036909
Consensus CDS Project	CCDS49797.1
International Mouse Knockout Project Status	Igf2bp2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025859	VEGA Gene Model | MGI Sequence Detail	104291	C57BL/6J
transcript	OTTMUST00000063721	VEGA | MGI Sequence Detail	3899	Not Applicable
polypeptide	OTTMUSP00000031555	VEGA | MGI Sequence Detail	592	Not Applicable

All sequences(58) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(307 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004087	K Homology domain
InterPro	IPR004088	K Homology domain, type 1
InterPro	IPR012677	Nucleotide-binding, alpha-beta plait
InterPro	IPR000504	RNA recognition motif domain
Protein Ontology	PR:000008944	insulin-like growth factor 2 mRNA-binding protein 2

References

(Earliest) J:52252 Nielsen J, et al., A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol. 1999 Feb;19(2):1262-70
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)

Other accession IDs

MGI:2442686