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Fam13a Gene Detail
Summary
  • Symbol
    Fam13a
  • Name
    family with sequence similarity 13, member A
  • Synonyms
    D430015B01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889842
    NCBI Gene: 58909
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:58933536-59024502 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 27.93 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    494 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889842
protein coding gene Chr6:58932090-59024549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030820
protein coding gene Chr6:58564256-58664878 (-)
A/J MGP_AJ_G0030787
protein coding gene Chr6:56032844-56122040 (-)
AKR/J MGP_AKRJ_G0030715
protein coding gene Chr6:57874037-57970696 (-)
BALB/cJ MGP_BALBcJ_G0030799
protein coding gene Chr6:56323153-56412936 (-)
C3H/HeJ MGP_C3HHeJ_G0030513
protein coding gene Chr6:57853069-57944777 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031257
protein coding gene Chr6:59851562-59945854 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028449
protein coding gene Chr6:53042897-53132515 (-)
CAST/EiJ MGP_CASTEiJ_G0029911
protein coding gene Chr6:57511712-57610152 (-)
CBA/J MGP_CBAJ_G0030486
protein coding gene Chr6:62354102-62443233 (-)
DBA/2J MGP_DBA2J_G0030637
protein coding gene Chr6:55739861-55830571 (-)
FVB/NJ MGP_FVBNJ_G0030590
protein coding gene Chr6:55283566-55376867 (-)
LP/J MGP_LPJ_G0030722
protein coding gene Chr6:58491725-58584384 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030625
protein coding gene Chr6:65009044-65102356 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031283
protein coding gene Chr6:57738295-57829908 (-)
PWK/PhJ MGP_PWKPhJ_G0029626
protein coding gene Chr6:55487263-55579562 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029453
protein coding gene Chr6:56943110-57034659 (-)
WSB/EiJ MGP_WSBEiJ_G0029992
protein coding gene Chr6:57930870-58022198 (-)



Homology
more
  • Human Ortholog
    FAM13A, family with sequence similarity 13 member A
  • Vertebrate Orthologs
    4
  • Human Ortholog
    FAM13A, family with sequence similarity 13 member A
    Orthology source: HGNC
  • Synonyms
    ARHGAP48, FAM13A1
  • Links
    NCBI Gene ID: 10144
    neXtProt AC: NX_O94988
    UniProt: O94988

  • Chr Location
    4q22.1; chr4:88725954-89111398 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit resistance to cigarrette-induced emphysema.
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58909 NCBI Gene Model | MGI Sequence Detail 90967 C57BL/6J ±  kb
transcript NM_153574 RefSeq | MGI Sequence Detail 4300 C57BL/6  
polypeptide Q8BGI4 UniProt | EBI | MGI Sequence Detail 693 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 59

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:258290 Wardhana DA, et al., Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1529-1534

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory