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Sall1
Gene Detail
Symbol

Name
ID
Sall1
sal-like 1 (Drosophila)
MGI:1889585
Synonyms
Msal-3
Feature Type
protein coding gene
Genetic Map
Chromosome 8
43.51 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:89027248-89044162 bp, - strand
From Ensembl annotation of GRCm38

  16915 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2230  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SALL1
Gene Tree: Sall1

Human
homologs
SALL1, spalt-like transcription factor 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6299
neXtProt AC: NX_Q9NSC2

Human Synonyms: HEL-S-89, HSAL1, Sal-1, TBS, ZNF794

Human Chr (Location): 16q12.1; chr16:51135975-51152316 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SALL1

Mutations,
alleles, and
phenotypes
All mutations/alleles(42) : Gene trapped(28) Targeted(14)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation exhibit kidney agenesis or dysgenesis and die perinatally. Homozygotes expressing only a truncated protein show renal agenesis, exencephaly, and limb defects; heterozygotes have hearing loss and cystic kidneys.
 
Human Diseases Modeled in Mice Using Sall1 (1)    Mutations Annotated to Human Diseases (2)   
Interactions
Sall1 interacts with 274 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (69 annotations)
Process branching involved in ureteric bud morphogenesis, embryonic digestive tract development, ...
Component chromocenter, cytoplasm, ...
Function beta-catenin binding, chromatin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (53 records)
Data Summary: Results (594)    Tissues (309)    Images (89)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 505
Northern blot 7
RT-PCR 59
RNase protection 23
cDNA source data(49)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA SALL1 ; Xenbase sall1 ; ZFIN sall1a    NEW 
Molecular
reagents
All nucleic(57) Genomic(3) cDNA(49) Primer pair(3) Other(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000031665 (Evidence)
Entrez Gene 58198 (Evidence)
UniGene 214361
DFCI TC1580889
DoTS DT.40142365, DT.110858080
NIA Mouse Gene Index U030082
Consensus CDS Project CCDS40427.1
International Mouse Phenotyping Consortium Status Sall1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031665 Ensembl Gene Model | MGI Sequence Detail 16915 C57BL/6J ±  kb
transcript ENSMUST00000034090 Ensembl | MGI Sequence Detail 5252 Not Applicable 
polypeptide ENSMUSP00000034090 Ensembl | MGI Sequence Detail 1323 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(4) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000014436 Sal-like protein 1
References
(Earliest) J:64306 Buck A, et al., Molecular cloning, chromosomal localization, and expression of the murine SALL1 ortholog Sall1. Cytogenet Cell Genet. 2000;89(3-4):150-3
(Latest) J:219797 Ranghini EJ, et al., Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms. Dev Biol. 2015 Mar 15;399(2):296-305
All references(93)
Disease annotation references (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory