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Cxcl13
Gene Detail
Symbol

Name
ID
Cxcl13
chemokine (C-X-C motif) ligand 13
MGI:1888499
Synonyms
4631412M08Rik, ANGIE2, BCA-1, BLC, Scyb13
Feature Type
protein coding gene
Genetic Map
Chromosome 5
47.29 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:95956939-95961068 bp, + strand
From NCBI annotation of GRCm38

  4130 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48431  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: CXCL13
Protein SuperFamily: CXC chemokine
Gene Tree: Cxcl13

Human
homologs
CXCL13, chemokine (C-X-C motif) ligand 13
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10563
neXtProt AC: NX_O43927

Human Synonyms: ANGIE, ANGIE2, BCA1, BCA-1, BLC, BLR1L, SCYB13

Human Chr (Location): 4q21; chr4:77511753-77611834 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Chemically induced (ENU)(1) Gene trapped(1) Targeted(2) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
B lymphocyte trafficking is impaired in homozygous mutant mice.
 
Interactions
Cxcl13 interacts with 135 markers (Mir10a, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (40 annotations)
Process activation of GTPase activity, B cell chemotaxis, ...
Component cytosol, extracellular region, ...
Function CCR10 chemokine receptor binding, chemokine activity, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (61)    Tissues (31)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 53
RT-PCR 8
cDNA source data(42)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase cxcl13    NEW 
Molecular
reagents
All nucleic(44) cDNA(42) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000023078 (Evidence)
Entrez Gene 55985 (Evidence)
UniGene 10116
DFCI TC1579376
DoTS DT.492182, DT.97349147, DT.97372674
NIA Mouse Gene Index U005820
Consensus CDS Project CCDS19447.1
International Mouse Phenotyping Consortium Status Cxcl13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 55985 NCBI Gene Model | MGI Sequence Detail 4130 C57BL/6J ±  kb
transcript NM_018866 RefSeq | MGI Sequence Detail 1162 C57BL/6 
polypeptide O55038 UniProt | EBI | MGI Sequence Detail 109 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(50 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001811 Chemokine interleukin-8-like domain
InterPro IPR001089 CXC chemokine
InterPro IPR018048 CXC chemokine, conserved site
Protein Ontology PR:000006067 C-X-C motif chemokine 13
Graphical View of Protein Domain Structure
References
(Earliest) J:45894 Gunn MD, et al., A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature. 1998 Feb 19;391(6669):799-803
(Latest) J:217542 Obata Y, et al., Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues. EMBO Rep. 2014 Dec;15(12):1297-304
All references(79)
Other
accession IDs
MGI:1918033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory