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Clec4n
Gene Detail
Symbol

Name
ID
Clec4n
C-type lectin domain family 4, member n
MGI:1861231
Synonyms
Clecsf10, dectin-2, Nkcl
Feature Type
protein coding gene
Genetic Map
Chromosome 6
58.30 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr6:123229843-123247021 bp, + strand
From VEGA annotation of GRCm38

  17179 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:84615  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle

Gene Tree: Clec4n

Human
homologs
Human Homolog CLEC6A, C-type lectin domain family 6, member A
NCBI Gene ID 93978
neXtProt AC  NX_Q6EIG7
Human Synonyms  CLEC4N, CLECSF10
Human Chr (Location)  chr12:8455995-8478330 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele have defective responses to Candida albicans.
 
Interactions
Clec4n interacts with 178 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process defense response to fungus, immune system process, ...
Component integral component of membrane, membrane
Function carbohydrate binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (15)    Tissues (13)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 15
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(9) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027044 (Evidence)
Ensembl Gene ModelENSMUSG00000023349 (Evidence)
Entrez Gene56620 (Evidence)
UniGene271782
DFCITC1587461, TC1603923, TC1596868
DoTSDT.99857747, DT.110486818, DT.101380167, DT.99857749
NIA Mouse Gene IndexU007385
Consensus CDS ProjectCCDS20512.1, CCDS51895.1, CCDS51896.1
International Mouse Knockout Project StatusClec4n
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027044 VEGA Gene Model | MGI Sequence Detail 17179 C57BL/6J ±  kb
transcript OTTMUST00000066844 VEGA | MGI Sequence Detail 1229 Not Applicable 
polypeptide OTTMUSP00000033554 VEGA | MGI Sequence Detail 209 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(6) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(131 from dbSNP Build 137)    SNPs within 2kb including multiple locations(133)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000001806 C-type lectin domain family 6 member A
References
(Earliest) J:55818 Fernandes MJ, et al., Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells. Cancer Res. 1999 Jun 1;59(11):2709-17
(Latest) J:209412 Viriyakosol S, et al., Neither dectin-2 nor the mannose receptor is required for resistance to Coccidioides immitis in mice. Infect Immun. 2014 Mar;82(3):1147-56
All references(39)
Other
accession IDs
MGI:1341853

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory