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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Clec4n
C-type lectin domain family 4, member n
MGI:1861231
27 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Clec4ntm1.2Mgne/Clec4ntm1.2Mgne
involves: C57BL/6 * C57BL/6J 		abnormal chemokine secretion J:209284
abnormal interferon secretion J:209284
abnormal interleukin secretion J:209284
abnormal macrophage physiology J:209284
abnormal neutrophil physiology J:209284
abnormal susceptibility to fungal infection J:209284
abnormal tumor necrosis factor secretion J:209284
decreased interferon-gamma secretion J:209284
decreased interleukin-17 secretion J:209284
decreased tumor necrosis factor secretion J:209284
impaired macrophage phagocytosis J:209284
impaired neutrophil phagocytosis J:209284
increased interferon-gamma secretion J:209284
increased interleukin-1 alpha secretion J:209284
increased interleukin-1 beta secretion J:209284
increased interleukin-6 secretion J:209284
increased interleukin-17 secretion J:209284
increased susceptibility to fungal infection J:209284
increased tumor necrosis factor secretion J:209284
Clec4ntm1Yiw/Clec4ntm1Yiw
B6.129P2-Clec4ntm1Yiw 		abnormal CD4-positive T cell differentiation J:160680
abnormal kidney pelvis morphology J:160680
decreased interferon-gamma secretion J:160680
decreased interleukin-6 secretion J:160680
decreased interleukin-10 secretion J:160680
decreased interleukin-12b secretion J:160680
decreased interleukin-17 secretion J:160680
decreased interleukin-23 secretion J:160680
decreased tumor necrosis factor secretion J:160680
hydronephrosis J:160680
increased susceptibility to infection induced morbidity/mortality J:160680
Clec4ntm1Yiw/Clec4ntm1Yiw
involves: 129P2/OlaHsd 		increased susceptibility to fungal infection J:209284
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory