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Dnah10 Gene Detail
Summary
  • Symbol
    Dnah10
  • Name
    dynein, axonemal, heavy chain 10
  • Synonyms
    Dnahc10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860299
    NCBI Gene: 56087
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:124725085-124834303 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      109219 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 63.78 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DNAH10, dynein axonemal heavy chain 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNAH10, dynein axonemal heavy chain 10
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 196385
    neXtProt AC: NX_Q8IVF4
    UniProt: Q8IVF4

  • Chr Location
    12q24.31; chr12:123761995-123935720 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 25816
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DNAH10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034141 VEGA Gene Model | MGI Sequence Detail 109219 C57BL/6J ±  kb
transcript OTTMUST00000086457 VEGA | MGI Sequence Detail 13862 Not Applicable  
polypeptide OTTMUSP00000046824 VEGA | MGI Sequence Detail 4534 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    508 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR011704 ATPase, dynein-related, AAA domain
    IPR026983 Dynein heavy chain
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region D5
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR004273 Dynein heavy chain domain
    IPR013594 Dynein heavy chain, domain-1
    IPR013602 Dynein heavy chain, domain-2
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 12
    Genomic 2
    cDNA 8
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory