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Snx3 Gene Detail
Summary
  • Symbol
    Snx3
  • Name
    sorting nexin 3
  • Synonyms
    SDP3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860188
    NCBI Gene: 54198
  • Gene Overview
    MyGene.info: SNX3
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:42502054-42535369 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 22.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860188
protein coding gene Chr10:42502030-42535381 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017185
protein coding gene Chr10:41217096-41252798 (+)
A/J MGP_AJ_G0017162
protein coding gene Chr10:40058612-40092760 (+)
AKR/J MGP_AKRJ_G0017122
protein coding gene Chr10:40663551-40700803 (+)
BALB/cJ MGP_BALBcJ_G0017124
protein coding gene Chr10:40120954-40154892 (+)
C3H/HeJ MGP_C3HHeJ_G0016945
protein coding gene Chr10:41010180-41046264 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017583
protein coding gene Chr10:42460109-42497283 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015279
protein coding gene Chr10:37914391-37947042 (+)
CAST/EiJ MGP_CASTEiJ_G0016524
protein coding gene Chr10:41204411-41246180 (+)
CBA/J MGP_CBAJ_G0016919
protein coding gene Chr10:44404312-44459741 (+)
DBA/2J MGP_DBA2J_G0017024
protein coding gene Chr10:39540486-39574814 (+)
FVB/NJ MGP_FVBNJ_G0017019
protein coding gene Chr10:39035848-39069922 (+)
LP/J MGP_LPJ_G0017101
protein coding gene Chr10:41204804-41245449 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017049
protein coding gene Chr10:45167878-45202798 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017620
protein coding gene Chr10:40647256-40684011 (+)
PWK/PhJ MGP_PWKPhJ_G0016304
protein coding gene Chr10:39414400-39455766 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016088
protein coding gene Chr10:40469036-40507856 (+)
WSB/EiJ MGP_WSBEiJ_G0016587
protein coding gene Chr10:40945865-40982149 (+)



Homology
more
  • Human Ortholog
    SNX3, sorting nexin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNX3, sorting nexin 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Grd19, MCOPS8, SDP3
  • Links
    NCBI Gene ID: 8724
    neXtProt AC: NX_O60493
    UniProt: O60493

  • Chr Location
    6q21; chr6:108211217-108261260 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54198 NCBI Gene Model | MGI Sequence Detail 33316 C57BL/6J ±  kb
transcript NM_017472 RefSeq | MGI Sequence Detail 1377 C57BL/6  
polypeptide O70492 UniProt | EBI | MGI Sequence Detail 162 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 229
    Genomic 1
    cDNA 226
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 45
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory