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Snx3
Gene Detail
Symbol

Name
ID
Snx3
sorting nexin 3
MGI:1860188
Synonyms
SDP3
Feature Type
protein coding gene
Genetic Map
Chromosome 10
22.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:42502030-42535381 bp, + strand
From VEGA annotation of GRCm38

  33352 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36144  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SNX3
Protein SuperFamily: sorting nexin, Snx3 type
Gene Tree: Snx3

Human
homologs
SNX3, sorting nexin 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8724
neXtProt AC: NX_O60493

Human Synonyms: Grd19, MCOPS8, SDP3

Human Chr (Location): 6q21; chr6:108211217-108261260 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(20) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Snx3 interacts with 140 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (42 annotations)
Process endocytosis, heme biosynthetic process, ...
Component clathrin-coated vesicle, cytoplasm, ...
Function lipid binding, phosphatidylinositol-3,5-bisphosphate binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (188)    Tissues (59)    Images (101)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 188
cDNA source data(224)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snx3    NEW 
Molecular
reagents
All nucleic(228) Genomic(1) cDNA(225) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000019461 (Evidence)
Ensembl Gene Model ENSMUSG00000019804 (Evidence)
Entrez Gene 54198 (Evidence)
UniGene 277870
DFCI TC1572609
DoTS DT.495885, DT.91372150
NIA Mouse Gene Index U011447
Consensus CDS Project CCDS23812.1
International Mouse Phenotyping Consortium Status Snx3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019461 VEGA Gene Model | MGI Sequence Detail 33352 C57BL/6J ±  kb
transcript OTTMUST00000046474 VEGA | MGI Sequence Detail 1401 Not Applicable 
polypeptide OTTMUSP00000020985 VEGA | MGI Sequence Detail 162 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(2) UniProt(6)
Polymorphisms
SNPs within 2kb(169 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
Protein Ontology PR:000015378 sorting nexin-3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:198605 Chua RY, et al., SNX3 recruits to phagosomes and negatively regulates phagocytosis in dendritic cells. Immunology. 2013 May;139(1):30-47
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory