Sequence Detail

ID/Version

O70492 Q78ZM0 (UniProt | EBI)

Last sequence update: 2026-01-28
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Sorting nexin-3;AltName: Full=SDP3 protein;

Provider

SWISS-PROT

Sequence

Polypeptide 162 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Snx3	sorting nexin 3	58	101	3	29

Sequence references in MGI

J:77888 Abrahams BS, et al., Novel Vertebrate Genes and Putative Regulatory Elements Identified at Kidney Disease and NR2E1/fierce Loci. Genomics. 2002 Jul;80(1):45-53
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:198162 Chen C, et al., Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 5;17(3):343-52
J:215881 Mizutani R, et al., Sorting nexin 3, a protein upregulated by lithium, contains a novel phosphatidylinositol-binding sequence and mediates neurite outgrowth in N1E-115 cells. Cell Signal. 2009 Nov;21(11):1586-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:299457 Brown HM, et al., Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling. Development. 2020 Nov 19;147(22):dev192518
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87