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Cdc20
Gene Detail
 Symbol
Name
ID
Cdc20
cell division cycle 20
MGI:1859866
Synonyms 2310042N09Rik, p55CDC
Feature Type protein coding gene
Genetic Map
Chromosome 4
54.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:118432901-118437352 bp, - strand
From VEGA annotation of GRCm38

  4452 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37459  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cdc20

Human
homologs
Human Homolog CDC20, cell division cycle 20
NCBI Gene ID 991
neXtProt AC  NX_Q12834
Human Synonyms  bA276H19.3, CDC20A, p55CDC
Human Chr (Location)  1p34.1; chr1:43358955-43363203 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(3) Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for mutations in this gene display embryonic lethality with cell cycle abnormalities. Mice heterozygous for a mutation in this gene display increased tumor incidence and increased incidence of aneuploidy.
 
Interactions
Cdc20 interacts with 8 markers (Mir101a, Mir101b, Mir101c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, ...
Component anaphase-promoting complex, centrosome, ...
Function enzyme binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (110)    Tissues (21)    Images (21)
Theiler Stages: 1, 2, 3, 20, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 62
Western blot 5
RT-PCR 43
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(13) Primer pair(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000008798 (Evidence)
Ensembl Gene ModelENSMUSG00000006398 (Evidence)
Entrez Gene107995 (Evidence)
NIA Mouse Gene IndexU025447, U089539, U373979
Consensus CDS ProjectCCDS18551.1
International Mouse Knockout Project StatusCdc20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008798 VEGA Gene Model | MGI Sequence Detail 4452 C57BL/6J ±  kb
transcript OTTMUST00000020001 VEGA | MGI Sequence Detail 1793 Not Applicable 
polypeptide OTTMUSP00000009177 VEGA | MGI Sequence Detail 499 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000005188 cell division cycle protein 20
References (Earliest) J:59059 Inbal N, et al., The mammalian Fizzy and Fizzy-related genes are regulated at the transcriptional and post-transcriptional levels. FEBS Lett. 1999 Dec 17;463(3):350-4
(Latest) J:198275 Watanabe N, et al., The REV7 subunit of DNA polymerase zeta is essential for primordial germ cell maintenance in the mouse. J Biol Chem. 2013 Apr 12;288(15):10459-71
All references(62)
Other
accession IDs
MGI:1913810, MGI:2146726

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory