Cdc20 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc20
cell division cycle 20
MGI:1859866

38 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc20^Gt(XE368)Byg/Cdc20^Gt(XE368)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal chromosome morphology	J:121535
	embryonic lethality before implantation, incomplete penetrance	J:121535
	embryonic lethality between implantation and somite formation, complete penetrance	J:121535
Cdc20^Gt(XE368)Byg/Cdc20^tm1Jvd involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal female meiosis	J:165500
	abnormal male germ cell morphology	J:165500
	abnormal oocyte morphology	J:165500
	aneuploidy	J:165500
	female infertility	J:165500
	maternal effect	J:165500
	reduced female fertility	J:165500
	normal reproductive system phenotype	J:165500
Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20⁺ B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J	decreased circulating glucose level	J:211773
	improved glucose tolerance	J:211773
	increased circulating glucose level	J:211773
	increased fasting circulating glucose level	J:211773
	increased grip strength	J:211773
	increased heart weight	J:211773
Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20^{tm1.1(KOMP)Vlcg} B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cdc20^tm1.1Mama/Cdc20^tm1.2Mama Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a⁺ involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL	abnormal epidermis stratum basale morphology	J:167609
	abnormal intestinal epithelium morphology	J:167609
	abnormal mitosis	J:167609
	decreased cell proliferation	J:167609
	decreased tumor growth/size	J:167609
	delayed hair regrowth	J:167609
	premature death	J:167609
	tumor regression	J:167609
	weight loss	J:167609
Cdc20^tm1.1Pzg/Cdc20⁺ involves: 129S7/SvEvBrd * C57BL/6	aneuploidy	J:150421
	increased hepatoma incidence	J:150421
	increased lymphoma incidence	J:150421
	increased tumor incidence	J:150421
Cdc20^tm1.1Pzg/Cdc20^tm1.1Pzg involves: 129S7/SvEvBrd * C57BL/6	abnormal cell death	J:150421
	abnormal mitosis	J:150421
	aneuploidy	J:150421
	decreased cell proliferation	J:150421
	decreased embryo size	J:150421
	embryonic lethality during organogenesis, complete penetrance	J:150421
	increased embryonic tissue cell apoptosis	J:150421
Cdc20^tm1.2Mama/Cdc20^tm1.2Mama involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL	embryonic lethality before implantation, complete penetrance	J:167609
	failure of zygotic cell division	J:167609
Cdc20^tm1Jvd/Cdc20^tm1Jvd involves: 129S6/SvEvTac * C57BL/6	normal reproductive system phenotype	J:165500

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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