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Azin1 Gene Detail
Summary
  • Symbol
    Azin1
  • Name
    antizyme inhibitor 1
  • Synonyms
    1700085L02Rik, Oazi, Oazin, ODC antizyme inhibitor
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859169
    NCBI Gene: 54375
  • Gene Overview
    MyGene.info: AZIN1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:38487427-38519266 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 15.17 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    118 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859169
protein coding gene Chr15:38487427-38519285 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021808
protein coding gene Chr15:37006658-37039515 (-)
A/J MGP_AJ_G0021768
protein coding gene Chr15:35575910-35607795 (-)
AKR/J MGP_AKRJ_G0021749
protein coding gene Chr15:36638461-36673936 (-)
BALB/cJ MGP_BALBcJ_G0021775
protein coding gene Chr15:35613131-35647685 (-)
C3H/HeJ MGP_C3HHeJ_G0021549
protein coding gene Chr15:36575683-36606638 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022214
protein coding gene Chr15:38438287-38471232 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019751
protein coding gene Chr15:33347645-33379112 (-)
CAST/EiJ MGP_CASTEiJ_G0021066
protein coding gene Chr15:36995767-37029683 (-)
CBA/J MGP_CBAJ_G0021518
protein coding gene Chr15:39666050-39700727 (-)
DBA/2J MGP_DBA2J_G0021642
protein coding gene Chr15:35410824-35445617 (-)
FVB/NJ MGP_FVBNJ_G0021620
protein coding gene Chr15:34817849-34849453 (-)
LP/J MGP_LPJ_G0021712
protein coding gene Chr15:36872094-36906439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021644
protein coding gene Chr15:42661944-42699150 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022237
protein coding gene Chr15:36765575-36800842 (-)
PWK/PhJ MGP_PWKPhJ_G0020810
protein coding gene Chr15:35469626-35501333 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020648
protein coding gene Chr15:36460878-36497659 (-)
WSB/EiJ MGP_WSBEiJ_G0021121
protein coding gene Chr15:36722503-36753518 (-)



Homology
more
  • Human Ortholog
    AZIN1, antizyme inhibitor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AZIN1, antizyme inhibitor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AZI, AZI1, AZIA1, OAZI, OAZIN, ODC1L
  • Links
    NCBI Gene ID: 51582
    neXtProt AC: NX_O14977
    UniProt: O14977

  • Chr Location
    8q22.3; chr8:102826302-102864200 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous disruption of this gene results in neonatal lethality, a slight reduction in birth weight, and abnormal liver morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037458 Ensembl Gene Model | MGI Sequence Detail 31840 C57BL/6J ±  kb
    transcript ENSMUST00000065308 Ensembl | MGI Sequence Detail 4871 Not Applicable  
    polypeptide ENSMUSP00000065544 Ensembl | MGI Sequence Detail 448 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 23
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1920775, MGI:2145992
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 4
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory