About   Help   FAQ
Rnf10
Gene Detail
Symbol

Name
ID
Rnf10
ring finger protein 10
MGI:1859162
Synonyms
mKIAA0262
Feature Type
protein coding gene
Genetic Map
Chromosome 5
56.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:115241412-115272898 bp, - strand
From VEGA annotation of GRCm38

  31487 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40990  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RNF10
Gene Tree: Rnf10

Human
homologs
RNF10, ring finger protein 10
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9921
neXtProt AC: NX_Q8N5U6

Human Synonyms: RIE2

Human Chr (Location): 12q24.31; chr12:120534308-120577594 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Endonuclease-mediated(1) Gene trapped(25) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rnf10 interacts with 112 markers (Mir7-2, Mir7b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process negative regulation of Schwann cell proliferation, positive regulation of myelination, ...
Component cytoplasm, nucleus
Function DNA binding, metal ion binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (14)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
cDNA source data(335)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rnf10    NEW 
Molecular
reagents
All nucleic(336) cDNA(335) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014638 (Evidence)
Ensembl Gene Model ENSMUSG00000041740 (Evidence)
Entrez Gene 50849 (Evidence)
UniGene 30051
DFCI TC1573183, TC1607554
DoTS DT.101237756, DT.103583870, DT.103583889, DT.110676091, DT.91330317, DT.99863867, DT.99863869, DT.99863871
NIA Mouse Gene Index U026625
Consensus CDS Project CCDS19584.1
International Mouse Phenotyping Consortium Status Rnf10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014638 VEGA Gene Model | MGI Sequence Detail 31487 C57BL/6J ±  kb
transcript OTTMUST00000034713 VEGA | MGI Sequence Detail 3476 Not Applicable 
polypeptide OTTMUSP00000015538 VEGA | MGI Sequence Detail 805 Not Applicable 

For the selected sequences
All sequences(103) RefSeq(8) UniProt(6)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000014064 RING finger protein 10
References
(Earliest) J:61756 Seki N, et al., cDNA cloning, expression profile, and genomic structure of human and mouse RNF10/Rnf 10 genes, encoding a novel RING finger protein. J Hum Genet. 2000;45(1):38-42
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:2140785

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory