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Cyp3a41a
Gene Detail
 Symbol
Name
ID
Cyp3a41a
cytochrome P450, family 3, subfamily a, polypeptide 41A
MGI:1858451
Synonyms Cyp3a41, steroid inducible
Feature Type protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:145694060-145720136 bp, - strand
From Ensembl annotation of GRCm38

  26077 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133568  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: trichodiene oxygenase
Gene Tree: Cyp3a41a

Human
homologs
Human Homolog CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
NCBI Gene ID 1577
neXtProt AC  NX_P20815
Human Synonyms  CP35, CYPIIIA5, P450PCN3, PCN3
Human Chr (Location)  7q21.1; chr7:99648190-99679998 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP3A5
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving Cyp3a41a (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp3a41a interacts with 107 markers (Mir10a, Mir15b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process demethylation, oxidation-reduction process, ...
Component endoplasmic reticulum membrane, intracellular membrane-bounded organelle
Function demethylase activity, oxidoreductase activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(15) Genomic(9) cDNA(6)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000075551 (Evidence)
Entrez Gene53973 (Evidence)
UniGene379071
DoTSDT.91337806
Consensus CDS ProjectCCDS19863.1
International Mouse Knockout Project StatusCyp3a41a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075551 Ensembl Gene Model | MGI Sequence Detail 26077 C57BL/6J ±  kb
transcript ENSMUST00000094111 Ensembl | MGI Sequence Detail 2049 Not Applicable 
polypeptide ENSMUSP00000091659 Ensembl | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(4)
Polymorphisms SNPs within 2kb(315 from dbSNP Build 137)    SNPs within 2kb including multiple locations(929)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006245 cytochrome P450 3A41
References (Earliest) J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
(Latest) J:146035 van Waterschoot RA, et al., Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 2009 Jan;23(1):224-31
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory