Cyp3a41a
Gene Detail

Symbol Name ID

Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A MGI:1858451

Synonyms

Cyp3a41, steroid inducible

Feature Type

protein coding gene

Genetic Map

Chromosome 5

85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:145694060-145720136 bp, - strand From Ensembl annotation of GRCm38   26077 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:121493  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: trichodiene oxygenase
Gene Tree: Cyp3a41a

Human homologs

Human Homolog		CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
NCBI Gene ID		1577
neXtProt AC		NX_P20815
Human Synonyms		CP35, CYPIIIA5, P450PCN3, PCN3
Human Chr (Location)		7q21.1; chr7:99245813-99277621 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP3A5

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	regulation of gene expression
Component	endoplasmic reticulum membrane, intracellular membrane-bounded organelle
Function	demethylase activity, oxidoreductase activity, ...

External Resources: FuncBase

Expression

cDNA source data(5)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(14) Genomic(9) cDNA(5)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000075551 (Evidence)
Entrez Gene	53973 (Evidence)
UniGene	379071
DoTS	DT.91337806
Consensus CDS Project	CCDS19863.1
International Mouse Knockout Project Status	Cyp3a41a

Sequences

Length	Strain/Species
genomic	ENSMUSG00000075551	Ensembl Gene Model | MGI Sequence Detail	26077	C57BL/6J
transcript	ENSMUST00000094111	Ensembl | MGI Sequence Detail	2049	Not Applicable
polypeptide	ENSMUSP00000091659	Ensembl | MGI Sequence Detail	504	Not Applicable

All sequences(14) RefSeq(4)

Polymorphisms

SNPs(7 from dbSNP Build 128)

References

(Earliest) J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
(Latest) J:146035 van Waterschoot RA, et al., Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 2009 Jan;23(1):224-31
All references(19)