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Cyp3a41a
Gene Detail
Symbol

Name
ID
Cyp3a41a
cytochrome P450, family 3, subfamily a, polypeptide 41A
MGI:1858451
Synonyms
Cyp3a41, steroid inducible
Feature Type
protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:145694060-145720136 bp, - strand
From Ensembl annotation of GRCm38

  26077 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133568  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: CYP3A5
Protein SuperFamily: trichodiene oxygenase
Gene Tree: Cyp3a41a

Human
homologs
CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1577
neXtProt AC: NX_P20815

Human Synonyms: CP35, CYPIIIA5, P450PCN3, PCN3

Human Chr (Location): 7q21.1; chr7:99648189-99680026 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CYP3A5

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving Cyp3a41a (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp3a41a interacts with 107 markers (Mir10a, Mir15b, Mir23a, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(6)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(15) Genomic(9) cDNA(6)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000075551 (Evidence)
Entrez Gene 53973 (Evidence)
UniGene 379071
DoTS DT.91337806
Consensus CDS Project CCDS19863.1
International Mouse Phenotyping Consortium Status Cyp3a41a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075551 Ensembl Gene Model | MGI Sequence Detail 26077 C57BL/6J ±  kb
transcript ENSMUST00000094111 Ensembl | MGI Sequence Detail 2049 Not Applicable 
polypeptide ENSMUSP00000091659 Ensembl | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(4)
Polymorphisms
SNPs within 2kb(315 from dbSNP Build 137)    SNPs within 2kb including multiple locations(929)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006245 cytochrome P450 3A41
References
(Earliest) J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
(Latest) J:146035 van Waterschoot RA, et al., Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 2009 Jan;23(1):224-31
All references(19)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory