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Cyp3a41a Gene Detail
Summary
  • Symbol
    Cyp3a41a
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 41A
  • Synonyms
    Cyp3a41, steroid inducible
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858451
    NCBI Gene: 53973
  • Gene Overview
    MyGene.info: CYP3A5
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr5:145694049-145720136 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 85.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858451
protein coding gene Chr5:145694049-145720136 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030369
protein coding gene Chr5:151307644-151351610 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0030065
protein coding gene Chr5:149739041-149815321 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0030139
protein coding gene Chr5:143352662-143850926 (-)
LP/J MGP_LPJ_G0030273
protein coding gene Chr5:151510312-151550177 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
    Orthology source: HomoloGene
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815
    UniProt: P20815

  • Chr Location
    7q22.1; chr7:99648189-99680026 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CYP3A5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 53973 NCBI Gene Model | MGI Sequence Detail 26088 C57BL/6J ±  kb
transcript NM_017396 RefSeq | MGI Sequence Detail 2060 Not Specified  
polypeptide Q9JMA7 UniProt | EBI | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 9
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
  • Latest
    J:247967 Kumar R, et al., Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLoS One. 2017;12(3):e0174355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory