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Cyp3a41a Gene Detail
Summary
  • Symbol
    Cyp3a41a
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 41A
  • Synonyms
    Cyp3a41, steroid inducible
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858451
    NCBI Gene: 53973
  • Gene Overview
    MyGene.info: CYP3A5
Location & Maps
more
  • Sequence Map
    Chr5:145694049-145720136 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26088 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 85.17 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815

  • Chr Location
    7q21.1; chr7:99648189-99680026 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CYP3A5 associations

Human Disease Mouse Models
       Hypertension, Essential   OMIM: 145500
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Cyp3a41a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Other Mouse Links
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055073 VEGA Gene Model | MGI Sequence Detail 26088 C57BL/6J ±  kb
transcript OTTMUST00000136403 VEGA | MGI Sequence Detail 2060 Not Applicable  
polypeptide OTTMUSP00000072005 VEGA | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    16 from dbSNP Build 142
Molecular
Reagents
less
  • All nucleic 15
    Genomic 9
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 18
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
  • Latest
    J:146035 van Waterschoot RA, et al., Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 2009 Jan;23(1):224-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory