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Csnk1d
Gene Detail
Symbol

Name
ID
Csnk1d
casein kinase 1, delta
MGI:1355272
Synonyms
1200006A05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
84.75 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:120961749-120991330 bp, - strand
From VEGA annotation of GRCm38

  29582 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74841  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CSNK1D
Protein SuperFamily: kinase-related transforming protein
Gene Tree: Csnk1d

Human
homologs
CSNK1D, casein kinase 1, delta
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1453
neXtProt AC: NX_P48730

Human Synonyms: ASPS, CKIdelta, FASPS2, HCKID

Human Chr (Location): 17q25; chr17:82239725-82273742 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CSNK1D

Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(9) Targeted(3) Transgenic(4)
 
Homozygous null mice die 1.5 to 5 days after birth and fetal weight is significantly smaller than controls.
 
Human Diseases Modeled in Mice Using Csnk1d (1)    Mutations Annotated to Human Diseases (3)   
Interactions
Csnk1d interacts with 274 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (42 annotations)
Process circadian regulation of gene expression, endocytosis, ...
Component centrosome, cytoplasm, ...
Function ATP binding, glycoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (102)    Tissues (69)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
Western blot 7
cDNA source data(327)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase csnk1d ; ZFIN csnk1da, csnk1db    NEW 
Molecular
reagents
All nucleic(332) cDNA(330) Primer pair(1) Other(1)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000004159 (Evidence)
Ensembl Gene Model ENSMUSG00000025162 (Evidence)
Entrez Gene 104318 (Evidence)
UniGene 216227
DFCI TC1597911, TC1585327, TC1573994
NIA Mouse Gene Index U033739
EC 2.7.11.1, 2.7.11.26
PDB 4JJR
Consensus CDS Project CCDS25762.1, CCDS25763.1
International Mouse Phenotyping Consortium Status Csnk1d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004159 VEGA Gene Model | MGI Sequence Detail 29582 C57BL/6J ±  kb
transcript OTTMUST00000009420 VEGA | MGI Sequence Detail 3675 Not Applicable 
polypeptide OTTMUSP00000004584 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(95) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000005945 casein kinase I isoform delta
References
(Earliest) J:54434 Leimeister C, et al., Screen for genes regulated during early kidney morphogenesis. Dev Genet. 1999;24(3-4):273-83
(Latest) J:220879 Greer YE, et al., Casein kinase 1delta functions at the centrosome and Golgi to promote ciliogenesis. Mol Biol Cell. 2014 May;25(10):1629-40
All references(55)
Disease annotation references (1)
Other
accession IDs
MGI:1918958, MGI:2143993

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory