aldehyde dehydrogenase family 1, subfamily A1
Mice homozygous for a disruption in this gene show a significantly reduced ability to convert retinol to retinoic acid in the liver. Retinal morphology is normal even though the gene is normally highly expressed in the dorsal retina.
|Process||9-cis-retinoic acid biosynthetic process, 9-cis-retinoic acid metabolic process, ...|
|Component||cytoplasm, extracellular vesicular exosome, ...|
|Function||3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ...|
|InterPro||IPR016160||Aldehyde dehydrogenase, conserved site|
|InterPro||IPR016163||Aldehyde dehydrogenase, C-terminal|
|InterPro||IPR015590||Aldehyde dehydrogenase domain|
|InterPro||IPR016162||Aldehyde dehydrogenase, N-terminal|
|Protein Ontology||PR:000003920||retinal dehydrogenase 1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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