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Homer2
Gene Detail
Symbol

Name
ID
Homer2
homer homolog 2 (Drosophila)
MGI:1347354
Synonyms
9330120H11Rik, CPD, Cupidin, Vesl-2
Feature Type
protein coding gene
Genetic Map
Chromosome 7
45.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:81600481-81706925 bp, - strand
From NCBI annotation of GRCm38

  106445 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3560  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Homer2

Human
homologs
Human Homolog HOMER2, homer homolog 2 (Drosophila)
NCBI Gene ID 9455
neXtProt AC  NX_Q9NSB8
Human Synonyms  ACPD, CPD, HOMER-2, VESL-2
Human Chr (Location)  15q24.3; chr15:82841086-82986161 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants exhibit an increase in intracellular calcium concentration and in the frequency of intracellular calcium oscillations in pancreatic acinar cells.
 
Interactions
Homer2 interacts with 561 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (150)    Tissues (42)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 105
Northern blot 8
Western blot 6
RT-PCR 26
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) cDNA(81) Primer pair(2) Other(2)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000025813 (Evidence)
Entrez Gene26557 (Evidence)
UniGene228
DFCITC1686163, TC1580770, TC1630616, TC1610736, TC1603711, TC1585109, TC1596409, TC1589253
DoTSDT.94325924, DT.111005514, DT.101707180, DT.101197127, DT.91446822, DT.40154868, DT.91303631, DT.87052348, DT.490590
NIA Mouse Gene IndexU028783, U028784, U028785
PDB1I7A
Consensus CDS ProjectCCDS40009.1, CCDS52284.1
International Mouse Knockout Project StatusHomer2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 26557 NCBI Gene Model | MGI Sequence Detail 106445 C57BL/6J ±  kb
transcript NM_011983 RefSeq | MGI Sequence Detail 10999 C57BL/6 
polypeptide Q9QWW1 UniProt | EBI | MGI Sequence Detail 354 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(9) UniProt(9)
Polymorphisms
SNPs within 2kb(1100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000697 EVH1
InterPro IPR011993 Pleckstrin homology-like domain
Protein Ontology PR:000008679 homer protein homolog 2
Graphical View of Protein Domain Structure
References
(Earliest) J:50718 Xiao B, et al., Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron. 1998 Oct;21(4):707-16
(Latest) J:200071 Park JM, et al., A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. Cell. 2013 Aug 1;154(3):637-50
All references(44)
Other
accession IDs
MGI:2142248, MGI:2442918

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory