Homozygous mice for one mutation were viable but showed reduced weight gain associated with decreased peripheral fat deposition. Mutant mice were resistant to high-fat diet induced obesity. Another targeted mutation resulted in no significant abnormalities in homozygotes.
|RNA in situ||260|
|In situ reporter (knock in)||92|
|InterPro||IPR008946||Nuclear hormone receptor, ligand-binding|
|InterPro||IPR000536||Nuclear hormone receptor, ligand-binding, core|
|InterPro||IPR024178||Oestrogen receptor/oestrogen-related receptor|
|InterPro||IPR001723||Steroid hormone receptor|
|InterPro||IPR013088||Zinc finger, NHR/GATA-type|
|InterPro||IPR001628||Zinc finger, nuclear hormone receptor-type|
|Protein Ontology||PR:000007208||steroid hormone receptor ERR1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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