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Mrps12 Gene Detail
Summary
  • Symbol
    Mrps12
  • Name
    mitochondrial ribosomal protein S12
  • Synonyms
    mitoribosomal protein s12, Rpms12, rps12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346333
    NCBI Gene: 24030
  • Gene Overview
    MyGene.info: MRPS12
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28739641-28741820 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346333
protein coding gene Chr7:28739641-28741899 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031956
protein coding gene Chr7:27567852-27573684 (-)
A/J MGP_AJ_G0031934
protein coding gene Chr7:26886179-26888414 (-)
AKR/J MGP_AKRJ_G0031866
protein coding gene Chr7:27576307-27580167 (-)
BALB/cJ MGP_BALBcJ_G0031941
protein coding gene Chr7:27045538-27047792 (-)
C3H/HeJ MGP_C3HHeJ_G0031660
protein coding gene Chr7:27954519-27956690 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032405
protein coding gene Chr7:28471426-28474404 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029457
protein coding gene Chr7:27946947-27949342 (-)
CAST/EiJ MGP_CASTEiJ_G0030995
protein coding gene Chr7:21273862-21276161 (-)
CBA/J MGP_CBAJ_G0031626
protein coding gene Chr7:29740217-29746385 (-)
DBA/2J MGP_DBA2J_G0031778
protein coding gene Chr7:26638777-26641974 (-)
FVB/NJ MGP_FVBNJ_G0031735
protein coding gene Chr7:26715216-26717461 (-)
LP/J MGP_LPJ_G0031858
protein coding gene Chr7:27897611-27901467 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031771
protein coding gene Chr7:29206769-29211732 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032435
protein coding gene Chr7:27055585-27059630 (-)
PWK/PhJ MGP_PWKPhJ_G0030720
protein coding gene Chr7:21663256-21665555 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030553
protein coding gene Chr7:18076250-18078423 (-)
WSB/EiJ MGP_WSBEiJ_G0031104
protein coding gene Chr7:27424013-27428781 (-)



Homology
more
  • Human Ortholog
    MRPS12, mitochondrial ribosomal protein S12
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MRPS12, mitochondrial ribosomal protein S12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12
  • Links
    NCBI Gene ID: 6183
    neXtProt AC: NX_O15235
    UniProt: O15235

  • Chr Location
    19q13.2; chr19:38930708-38933020 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045948 Ensembl Gene Model | MGI Sequence Detail 2180 C57BL/6J ±  kb
transcript ENSMUST00000171183 Ensembl | MGI Sequence Detail 883 Not Applicable  
polypeptide ENSMUSP00000132443 Ensembl | MGI Sequence Detail 139 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141924
References
more
  • Summaries
    All 31
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:57556 Shah ZH, et al., Metazoan nuclear genes for mitoribosomal protein S12. Gene. 1997 Dec 19;204(1-2):55-62
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory