About   Help   FAQ
Mrps12 Gene Detail
Summary
  • Symbol
    Mrps12
  • Name
    mitochondrial ribosomal protein S12
  • Synonyms
    mitoribosomal protein s12, Rpms12, rps12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346333
    NCBI Gene: 24030
  • Gene Overview
    MyGene.info: MRPS12
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28439066-28441245 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346333
protein coding gene Chr7:28439066-28441246 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031956
protein coding gene Chr7:27567852-27573684 (-)
A/J MGP_AJ_G0031934
protein coding gene Chr7:26886179-26888414 (-)
AKR/J MGP_AKRJ_G0031866
protein coding gene Chr7:27576307-27580167 (-)
BALB/cJ MGP_BALBcJ_G0031941
protein coding gene Chr7:27045538-27047792 (-)
C3H/HeJ MGP_C3HHeJ_G0031660
protein coding gene Chr7:27954519-27956690 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032405
protein coding gene Chr7:28471426-28474404 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029457
protein coding gene Chr7:27946947-27949342 (-)
CAST/EiJ MGP_CASTEiJ_G0030995
protein coding gene Chr7:21273862-21276161 (-)
CBA/J MGP_CBAJ_G0031626
protein coding gene Chr7:29740217-29746385 (-)
DBA/2J MGP_DBA2J_G0031778
protein coding gene Chr7:26638777-26641974 (-)
FVB/NJ MGP_FVBNJ_G0031735
protein coding gene Chr7:26715216-26717461 (-)
LP/J MGP_LPJ_G0031858
protein coding gene Chr7:27897611-27901467 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031771
protein coding gene Chr7:29206769-29211732 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032435
protein coding gene Chr7:27055585-27059630 (-)
PWK/PhJ MGP_PWKPhJ_G0030720
protein coding gene Chr7:21663256-21665555 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030553
protein coding gene Chr7:18076250-18078423 (-)
WSB/EiJ MGP_WSBEiJ_G0031104
protein coding gene Chr7:27424013-27428781 (-)



Homology
more
  • Human Ortholog
    MRPS12, mitochondrial ribosomal protein S12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPS12, mitochondrial ribosomal protein S12
  • Synonyms
    MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12
  • Links
    NCBI Gene ID: 6183
    neXtProt AC: NX_O15235
    UniProt: O15235

  • Chr Location
    19q13.2; chr19:38930708-38933020 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045948 Ensembl Gene Model | MGI Sequence Detail 2180 C57BL/6J ±  kb
transcript ENSMUST00000171183 Ensembl | MGI Sequence Detail 883 Not Applicable  
polypeptide ENSMUSP00000132443 Ensembl | MGI Sequence Detail 139 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 76
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141924
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:57556 Shah ZH, et al., Metazoan nuclear genes for mitoribosomal protein S12. Gene. 1997 Dec 19;204(1-2):55-62
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/19/2021
MGI 6.17
The Jackson Laboratory