Mrps12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrps12
mitochondrial ribosomal protein S12
MGI:1346333

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrps12^em1(IMPC)Bay/Mrps12⁺ C57BL/6N-Mrps12^em1(IMPC)Bay/BayMmucd	decreased exploration in new environment	J:211773
Mrps12^em1(IMPC)Bay/Mrps12^em1(IMPC)Bay C57BL/6N-Mrps12^em1(IMPC)Bay/BayMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Mrps12^em1.2Afi/Mrps12^em1.2Afi B6N(Cg)-Mrps12^em1.2Afi	abnormal hepatocyte morphology	J:284101
	abnormal mitochondrial ATP synthesis coupled electron transport	J:284101
	abnormal translation	J:284101
	increased cholesterol level	J:284101
	increased hepatocyte proliferation	J:284101
	increased mitochondrial DNA content	J:284101
Mrps12^em2.2Afi/Mrps12^em2.2Afi B6N(Cg)-Mrps12^em2.2Afi	abnormal heart left ventricle size	J:284101
	abnormal mitochondrial ATP synthesis coupled electron transport	J:284101
	abnormal mitochondrial physiology	J:284101
	abnormal translation	J:284101
	normal cellular phenotype	J:284101
	decreased cardiac muscle contractility	J:284101
	dilated cardiomyopathy	J:284101
	small heart	J:284101

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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