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Rnf144a Gene Detail
Summary
  • Symbol
    Rnf144a
  • Name
    ring finger protein 144A
  • Synonyms
    Rnf144, UIP4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344401
    NCBI Gene: 108089
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:26306794-26415320 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 9.69 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1896 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344401
protein coding gene Chr12:26300964-26415320 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019636
protein coding gene Chr12:24037588-24148042 (-)
A/J MGP_AJ_G0019603
protein coding gene Chr12:23401110-23518910 (-)
AKR/J MGP_AKRJ_G0019574
protein coding gene Chr12:24164008-24274692 (-)
BALB/cJ MGP_BALBcJ_G0019580
protein coding gene Chr12:23644007-23753358 (-)
C3H/HeJ MGP_C3HHeJ_G0019384
protein coding gene Chr12:24047086-24165079 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020028
protein coding gene Chr12:24803634-24919529 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017652
protein coding gene Chr12:22839554-22952145 (-)
CAST/EiJ MGP_CASTEiJ_G0018939
protein coding gene Chr12:19033995-19146293 (-)
CBA/J MGP_CBAJ_G0019355
protein coding gene Chr12:25587864-25707506 (-)
DBA/2J MGP_DBA2J_G0019469
protein coding gene Chr12:23224973-23332375 (-)
FVB/NJ MGP_FVBNJ_G0019460
protein coding gene Chr12:23095954-23205589 (-)
LP/J MGP_LPJ_G0019539
protein coding gene Chr12:24098548-24212797 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019495
protein coding gene Chr12:25379329-25493110 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020067
protein coding gene Chr12:23718310-23829353 (-)
PWK/PhJ MGP_PWKPhJ_G0018706
protein coding gene Chr12:17974175-18084763 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018494
protein coding gene Chr12:18225015-18332927 (-)
WSB/EiJ MGP_WSBEiJ_G0018990
protein coding gene Chr12:23902071-24016919 (-)



Homology
more
  • Human Ortholog
    RNF144A, ring finger protein 144A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RNF144A, ring finger protein 144A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hUIP4, RNF144, UBCE7IP4
  • Links
    NCBI Gene ID: 9781
    neXtProt AC: NX_P50876
    UniProt: P50876

  • Chr Location
    2p25.1; chr2:6917392-7076886 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108089 NCBI Gene Model | MGI Sequence Detail 108527 C57BL/6J ±  kb
transcript NM_001081977 RefSeq | MGI Sequence Detail 5189 C57BL/6  
polypeptide Q925F3 UniProt | EBI | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144788
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:56275 Martinez-Noel G, et al., A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. FEBS Lett. 1999 Jul 9;454(3):257-61
  • Latest
    J:267523 Ho SR, et al., RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. J Biol Chem. 2018 Oct 19;293(42):16307-16323

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory