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Rnf216 Gene Detail
Summary
  • Symbol
    Rnf216
  • Name
    ring finger protein 216
  • Synonyms
    2810055G22Rik, F830018F18Rik, Ubce7ip1, UIP83
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344349
    NCBI Gene: 108086
  • Gene Overview
    MyGene.info: RNF216
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:142990893-143112994 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 81.86 cM, cytoband G2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    419 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344349
protein coding gene Chr5:142990893-143113102 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030321
protein coding gene Chr5:148297051-148425237 (-)
A/J MGP_AJ_G0030290
protein coding gene Chr5:141929596-142050283 (-)
AKR/J MGP_AKRJ_G0030222
protein coding gene Chr5:146354928-146490458 (-)
BALB/cJ MGP_BALBcJ_G0030307
protein coding gene Chr5:143173290-143294050 (-)
C3H/HeJ MGP_C3HHeJ_G0030018
protein coding gene Chr5:147178922-147303862 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030752
protein coding gene Chr5:153704836-153835585 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027970
protein coding gene Chr5:135726518-135841117 (-)
CAST/EiJ MGP_CASTEiJ_G0029423
protein coding gene Chr5:146664084-146786646 (-)
CBA/J MGP_CBAJ_G0029988
protein coding gene Chr5:160014392-160154772 (-)
DBA/2J MGP_DBA2J_G0030138
protein coding gene Chr5:141688606-141806497 (-)
FVB/NJ MGP_FVBNJ_G0030093
protein coding gene Chr5:140897266-141015893 (-)
LP/J MGP_LPJ_G0030224
protein coding gene Chr5:148892431-149016093 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030124
protein coding gene Chr5:162481548-162599149 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030792
protein coding gene Chr5:146214400-146337690 (-)
PWK/PhJ MGP_PWKPhJ_G0029138
protein coding gene Chr5:140779258-140896668 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028974
protein coding gene Chr5:143964826-144081618 (-)
WSB/EiJ MGP_WSBEiJ_G0029497
protein coding gene Chr5:147014838-147137136 (-)



Homology
more
  • Human Ortholog
    RNF216, ring finger protein 216
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RNF216, ring finger protein 216
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN
  • Links
    NCBI Gene ID: 54476
    neXtProt AC: NX_Q9NWF9
    UniProt: Q9NWF9

  • Chr Location
    7p22.1; chr7:5620041-5781730 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19442
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RNF216
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045078 Ensembl Gene Model | MGI Sequence Detail 122102 C57BL/6J ±  kb
transcript ENSMUST00000200607 Ensembl | MGI Sequence Detail 3704 Not Applicable  
polypeptide ENSMUSP00000143705 Ensembl | MGI Sequence Detail 910 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
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MGI:1914459, MGI:2140947, MGI:2141046, MGI:2141333, MGI:2442239
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:56275 Martinez-Noel G, et al., A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. FEBS Lett. 1999 Jul 9;454(3):257-61
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory