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Ggps1 Gene Detail
Summary
  • Symbol
    Ggps1
  • Name
    geranylgeranyl diphosphate synthase 1
  • Synonyms
    1810026C22Rik, 9530089B04Rik, GGPP synthase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341724
    NCBI Gene: 14593
  • Gene Overview
    MyGene.info: GGPS1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr13:14050659-14063488 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12830 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.29 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GGPS1, geranylgeranyl diphosphate synthase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GGPS1, geranylgeranyl diphosphate synthase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GGPPS, GGPPS1
  • Links
    NCBI Gene ID: 9453
    neXtProt AC: NX_O95749
    UniProt: O95749

  • Chr Location
    1q42.3; chr1:235328438-235344532 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021302 Ensembl Gene Model | MGI Sequence Detail 12830 C57BL/6J ±  kb
transcript ENSMUST00000170957 Ensembl | MGI Sequence Detail 4244 Not Applicable  
polypeptide ENSMUSP00000126603 Ensembl | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    66 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 31
    Genomic 6
    cDNA 23
    Primer pair 2

    Microarray probesets 10
Other
Accession IDs
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MGI:1916424, MGI:1925988, MGI:2145293, MGI:2145506
References
more
  • Summaries
    All 53
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 19
  • Earliest
    J:54347 Kainou T, et al., Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human. Biochim Biophys Acta. 1999 Mar 25;1437(3):333-40
  • Latest
    J:238704 Jiang C, et al., GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017 Jan;13(1):e1006535

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory