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Gene Expression Literature Summary
Symbol
Name
ID
Ggps1
geranylgeranyl diphosphate synthase 1
MGI:1341724

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E18.5 P
Immunohistochemistry (section) 1 2 1 1 2 1 1 1 2 2 1
In situ RNA (section) 1
Western blot 1 1 1 2 2 1 1 1 1 2 3
RT-PCR 1 1 1 2 2 1 2 1 1 3 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ggps1  geranylgeranyl diphosphate synthase 1   (Synonyms: 1810026C22Rik, 9530089B04Rik, GGPP synthase)
Results  Reference
23*J:316204 Chen Z, Xu N, Chong D, Guan S, Jiang C, Yang Z, Li C, Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
3J:333325 Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, Zhang W, Zhang S, Zhang L, Yuan Y, Li C, Chen G, Xue B, Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023 Feb 13;16(1):24
3J:336898 Edwards W, Greco TM, Miner GE, Barker NK, Herring L, Cohen S, Cristea IM, Conlon FL, Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development. Dev Cell. 2023 Jun 19;58(12):1087-1105.e4
17J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65
1J:224387 Sisecioglu M, Budak H, Geffers L, Cankaya M, Ciftci M, Thaller C, Eichele G, Kufrevioglu OI, Ozdemir H, A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo. J Lipid Res. 2015 Aug;56(8):1551-9
3*J:299531 Wei L, Zheng YY, Sun J, Wang P, Tao T, Li Y, Chen X, Sang Y, Chong D, Zhao W, Zhou Y, Wang Y, Jiang Z, Qiu T, Li CJ, Zhu MS, Zhang X, GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism. J Biol Chem. 2020 Nov 20;295(47):15988-16001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory