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Adgrg1
Gene Detail
Symbol

Name
ID
Adgrg1
adhesion G protein-coupled receptor G1
MGI:1340051
Synonyms
Cyt28, Gpr56
Feature Type
protein coding gene
Genetic Map
Chromosome 8
47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:94977109-95014208 bp, + strand
From Ensembl annotation of GRCm38

  37100 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: ADGRG1
Protein SuperFamily: G protein-coupled receptor 56
Gene Tree: Adgrg1

Human
homologs
ADGRG1, adhesion G protein-coupled receptor G1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9289
neXtProt AC: NX_Q9Y653

Human Synonyms: BFPP, BPPR, GPR56, TM7LN4, TM7XN1

Human Chr (Location): 16q21; chr16:57619535-57665039 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human ADGRG1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null allele exhibit neuronal ectopias in the frontoparietal cortex due to disruptions in the pial basement membrane.
 
Interactions
Adgrg1 interacts with 180 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process angiogenesis, brain development, ...
Component extracellular exosome, extracellular region, ...
Function collagen binding, extracellular matrix binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (522)    Tissues (101)    Images (75)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 520
cDNA source data(132)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100490972 ; ZFIN adgrg1    NEW 
Molecular
reagents
All nucleic(138) Genomic(1) cDNA(135) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000031785 (Evidence)
Entrez Gene 14766 (Evidence)
UniGene 290834
DFCI TC1587656, TC1730408, TC1572574
DoTS DT.534001, DT.101323809
NIA Mouse Gene Index U009679
Consensus CDS Project CCDS22553.1
International Mouse Phenotyping Consortium Status Adgrg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031785 Ensembl Gene Model | MGI Sequence Detail 37100 C57BL/6J ±  kb
transcript ENSMUST00000179619 Ensembl | MGI Sequence Detail 3605 Not Applicable 
polypeptide ENSMUSP00000137520 Ensembl | MGI Sequence Detail 687 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(36) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(521 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017981 GPCR, family 2-like
InterPro IPR003910 GPCR, family 2, orphan receptor, GPR56
InterPro IPR000832 GPCR, family 2, secretin-like
InterPro IPR000203 GPS domain
Protein Ontology PR:000008189 G-protein coupled receptor 56
References
(Earliest) J:53199 Liu M, et al., GPR56, a novel secretin-like human G-protein-coupled receptor gene. Genomics. 1999 Feb 1;55(3):296-305
(Latest) J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory