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Gpr56
Gene Detail
Symbol

Name
ID
Gpr56
G protein-coupled receptor 56
MGI:1340051
Synonyms
Cyt28
Feature Type
protein coding gene
Genetic Map
Chromosome 8
47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:94977109-95014208 bp, + strand
From Ensembl annotation of GRCm38

  37100 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: G protein-coupled receptor 56
Gene Tree: Gpr56

Human
homologs
Human Homolog GPR56, G protein-coupled receptor 56
NCBI Gene ID 9289
neXtProt AC  NX_Q9Y653
Human Synonyms  BFPP, BPPR, TM7LN4, TM7XN1
Human Chr (Location)  16q13; chr16:57619530-57665032 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human GPR56
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit neuronal ectopias in the frontoparietal cortex due to disruptions in the pial basement membrane.
 
Interactions
Gpr56 interacts with 180 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process angiogenesis, brain development, ...
Component extracellular region, extracellular vesicular exosome, ...
Function collagen binding, extracellular matrix binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (522)    Tissues (101)    Images (75)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 520
cDNA source data(132)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(138) Genomic(1) cDNA(135) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000031785 (Evidence)
Entrez Gene14766 (Evidence)
UniGene290834
DFCITC1572574, TC1730408, TC1587656
DoTSDT.101323809, DT.534001
NIA Mouse Gene IndexU009679
Consensus CDS ProjectCCDS22553.1
International Mouse Knockout Project StatusGpr56
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031785 Ensembl Gene Model | MGI Sequence Detail 37100 C57BL/6J ±  kb
transcript ENSMUST00000179619 Ensembl | MGI Sequence Detail 3605 Not Applicable 
polypeptide ENSMUSP00000137520 Ensembl | MGI Sequence Detail 687 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(44) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(521 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017981 GPCR, family 2-like
InterPro IPR003910 GPCR, family 2, orphan receptor, GPR56
InterPro IPR000832 GPCR, family 2, secretin-like
InterPro IPR000203 GPS domain
Protein Ontology PR:000008189 G-protein coupled receptor 56
References
(Earliest) J:53199 Liu M, et al., GPR56, a novel secretin-like human G-protein-coupled receptor gene. Genomics. 1999 Feb 1;55(3):296-305
(Latest) J:209144 Bae BI, et al., Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science. 2014 Feb 14;343(6172):764-8
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory