Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables several functions, including collagen binding activity; extracellular matrix binding activity; and heparin binding activity. Involved in several processes, including Rho-activating G protein-coupled receptor signaling pathway; negative regulation of ferroptosis; and positive regulation of Rho protein signal transduction. Acts upstream of or within cerebral cortex regionalization; hematopoietic stem cell homeostasis; and positive regulation of neural precursor cell proliferation. Located in glial limiting end-foot. Is active in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in bilateral frontoparietal polymicrogyria and complex cortical dysplasia with other brain malformations 14B. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1).

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Gene Ontology Evidence Code Abbreviations:

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