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Csf2ra
Gene Detail
Symbol

Name
ID
Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
MGI:1339754
Synonyms
CD116, Csfgmra, GM-CSF-Ra, GM-CSFRalpha
Feature Type
protein coding gene
Genetic Map
Chromosome 19
56.89 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr19:61224402-61228418 bp, - strand
From NCBI annotation of GRCm38

  4017 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48406  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 3 chicken; 2 western clawed frog

Gene Tree: Csf2ra

Human
homologs
Human Homolog CSF2RA, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
NCBI Gene ID 1438
neXtProt AC  NX_P15509
Human Synonyms  CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GMCSFR, GM-CSF-R-alpha, GMR, SMDP4
Human Chr (Location)  XYp22.32 and Yp11.3
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(12)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Csf2ra interacts with 60 markers (Mir29a, Mir30b, Mir33, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Component integral component of membrane, membrane
Function cytokine receptor activity
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (29)    Tissues (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 23
RNase protection 6
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(16) Primer pair(5) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000059326 (Evidence)
Entrez Gene12982 (Evidence)
UniGene287228
DFCITC1586253
DoTSDT.101355619, DT.40169944
NIA Mouse Gene IndexU039215
Consensus CDS ProjectCCDS29946.1
International Mouse Knockout Project StatusCsf2ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12982 NCBI Gene Model | MGI Sequence Detail 4017 C57BL/6J ±  kb
transcript NM_009970 RefSeq | MGI Sequence Detail 1850 C57BL/6 
polypeptide Q00941 UniProt | EBI | MGI Sequence Detail 388 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(17) UniProt(4)
Polymorphisms
RFLP(3) : SNPs within 2kb(23 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015321 Interleukin-6 receptor alpha chain, binding
InterPro IPR003532 Short hematopoietin receptor, family 2, conserved site
Protein Ontology PR:000001354 granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Graphical View of Protein Domain Structure
References
(Earliest) J:11258 Kitamura T, et al., Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5082-6
(Latest) J:152946 Sferruzzi-Perri AN, et al., Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. Biol Reprod. 2009 Jul;81(1):207-21
All references(46)
Other
accession IDs
MGD-MRK-2188, MGI:88532

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory