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Csf2ra
Gene Detail
Symbol

Name
ID
Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
MGI:1339754
Synonyms
CD116, Csfgmra, GM-CSF-Ra, GM-CSFRalpha
Feature Type
protein coding gene
Genetic Map
Chromosome 19
56.89 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr19:61224402-61228418 bp, - strand
From Ensembl annotation of GRCm38

  4017 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48406  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 3 chicken; 2 western clawed frog

HCOP human homology predictions: CSF2RA
Gene Tree: Csf2ra

Human
homologs
CSF2RA, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1438
neXtProt AC: NX_P15509

Human Synonyms: CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GMCSFR, GM-CSF-R-alpha, GMR, SMDP4

Human Chr (Location): XYp22.32 and Yp11.3

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(12)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Csf2ra interacts with 60 markers (Mir29a, Mir30b, Mir33, ...)
Expression
Literature Summary: (8 records)
Data Summary: Results (29)    Tissues (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 23
RNase protection 6
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(16) Primer pair(5) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000059326 (Evidence)
Entrez Gene 12982 (Evidence)
UniGene 287228
DFCI TC1586253
DoTS DT.40169944, DT.101355619
NIA Mouse Gene Index U039215
Consensus CDS Project CCDS29946.1
International Mouse Phenotyping Consortium Status Csf2ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059326 Ensembl Gene Model | MGI Sequence Detail 4017 C57BL/6J ±  kb
transcript ENSMUST00000076046 Ensembl | MGI Sequence Detail 1849 Not Applicable 
polypeptide ENSMUSP00000075423 Ensembl | MGI Sequence Detail 388 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(19) UniProt(4)
Polymorphisms
RFLP(3) : SNPs within 2kb(23 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015321 Interleukin-6 receptor alpha chain, binding
InterPro IPR003532 Short hematopoietin receptor, family 2, conserved site
Protein Ontology PR:000001354 granulocyte-macrophage colony-stimulating factor receptor subunit alpha
References
(Earliest) J:11258 Kitamura T, et al., Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5082-6
(Latest) J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
All references(46)
Other
accession IDs
MGD-MRK-2188, MGI:88532

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory