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Purb Gene Detail
Summary
  • Symbol
    Purb
  • Name
    purine rich element binding protein B
  • Synonyms
    2310015K15Rik, Cager-2, D11Bwg0414e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338779
    NCBI Gene: 19291
  • Gene Overview
    MyGene.info: PURB
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6467599-6475917 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 4.16 cM, cytoband A1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338779
protein coding gene Chr11:6467599-6476076 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018024
protein coding gene Chr11:3590235-3598453 (-)
A/J MGP_AJ_G0017997
protein coding gene Chr11:3432536-3441401 (-)
AKR/J MGP_AKRJ_G0017961
protein coding gene Chr11:3604857-3613176 (-)
BALB/cJ MGP_BALBcJ_G0017965
protein coding gene Chr11:3442061-3450379 (-)
C3H/HeJ MGP_C3HHeJ_G0017778
protein coding gene Chr11:3477705-3485951 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018417
protein coding gene Chr11:3690805-3699123 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016075
protein coding gene Chr11:3318317-3326615 (-)
CAST/EiJ MGP_CASTEiJ_G0017340
protein coding gene Chr11:3474490-3482791 (-)
CBA/J MGP_CBAJ_G0017753
protein coding gene Chr11:4111477-4119589 (-)
DBA/2J MGP_DBA2J_G0017863
protein coding gene Chr11:3347966-3356234 (-)
FVB/NJ MGP_FVBNJ_G0017855
protein coding gene Chr11:3366729-3374940 (-)
LP/J MGP_LPJ_G0017934
protein coding gene Chr11:3662132-3670450 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017881
protein coding gene Chr11:3645653-3657070 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018457
protein coding gene Chr11:3629068-3637386 (-)
PWK/PhJ MGP_PWKPhJ_G0017120
protein coding gene Chr11:3382229-3390498 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016917
protein coding gene Chr11:3566830-3575106 (-)
WSB/EiJ MGP_WSBEiJ_G0017394
protein coding gene Chr11:3445565-3453772 (-)



Homology
more
  • Human Ortholog
    PURB, purine rich element binding protein B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PURB, purine rich element binding protein B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PURBETA
  • Links
    NCBI Gene ID: 5814
    neXtProt AC: NX_Q96QR8
    UniProt: Q96QR8

  • Chr Location
    7p13; chr7:44876293-44885385 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000094483 Ensembl Gene Model | MGI Sequence Detail 8319 C57BL/6J ±  kb
transcript ENSMUST00000179343 Ensembl | MGI Sequence Detail 8319 Not Applicable  
polypeptide ENSMUSP00000136957 Ensembl | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 1
    cDNA 14
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGD-MRK-34063, MGI:106370, MGI:1923687, MGI:3034759
References
more
  • Summaries
    All 44
    Developmental Gene Expression 3
    Gene Ontology 11
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:203492 Rumora AE, et al., Structural basis of multisite single-stranded DNA recognition and ACTA2 repression by purine-rich element binding protein B (Purbeta). Biochemistry. 2013 Jul 2;52(26):4439-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory