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Purb Gene Detail
Summary
  • Symbol
    Purb
  • Name
    purine rich element binding protein B
  • Synonyms
    2310015K15Rik, Cager-2, D11Bwg0414e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338779
    NCBI Gene: 19291
  • Gene Overview
    MyGene.info: PURB
Location & Maps
more
  • Genetic Map
    Chromosome 11, 4.16 cM, cytoband A1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    PURB, purine rich element binding protein B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PURB, purine rich element binding protein B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PURBETA
  • Links
    NCBI Gene ID: 5814
    neXtProt AC: NX_Q96QR8

  • Chr Location
    7p13; chr7:44876293-44885385 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005110 VEGA Gene Model | MGI Sequence Detail 8319 C57BL/6J ±  kb
transcript OTTMUST00000011438 VEGA | MGI Sequence Detail 8319 Not Applicable  
polypeptide OTTMUSP00000005331 VEGA | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    10 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013495 transcriptional activator protein Pur-beta
  • InterPro Domains
    IPR030499 Purine-rich element-binding protein beta
    IPR006628 Purine-rich element binding protein family
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 12
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGD-MRK-34063, MGI:106370, MGI:1923687, MGI:3034759
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 9
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:203492 Rumora AE, et al., Structural basis of multisite single-stranded DNA recognition and ACTA2 repression by purine-rich element binding protein B (Purbeta). Biochemistry. 2013 Jul 2;52(26):4439-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory